Postdoctoral Research Fellow in Epidemiology, Bordeaux Population Health Research Center, team ELEANOR, INSERM U1219, Univ Bordeaux

RESEARCH EXPERIENCE

 

  • Bordeaux Population Health Research Center (team ELEANOR),  INSERM U1219, Univ Bordeaux, France  & Research Institute for Environmental and Occupational Health (team 9), INSERM U1085, EHESP, Univ Rennes
    • Since Apr 2022 : Postdoctoral Research Fellow
  • François Baclesse Cancer Center, ANTICIPE INSERM U1086, Caen, France
    • Nov 2020 – Mar 2022 : Biostatistian
  • Rush University Medical Center, Rush Institute for Healthy Aging, Chicago, United States
    • Mar 2020 – Oct 2020 : Postdoctoral Research Fellow
  • Bordeaux Population Health Research Center (team LEHA),  INSERM U1219, Univ Bordeaux, France
    • Nov 2019 – Feb 2020 : Postdoctoral Research Fellow
    • Oct 2016 – Oct 2019 : PhD Fellow (Supervision: C. Samieri)
    • Feb 2016 – Sept 2016 : MSc Training Course

EDUCATION

  • Oct 2019 : Public Health – Epidemiology, PhD, University of Bordeaux, Bordeaux, France
  • Sept 2016 : Agri-Food Sciences, MSc (French Engineering Degree), Agrocampus Ouest, Rennes, France
  • Sept 2016 : Applied Statistics, MSc, University of Rennes 2 – Agrocampus Ouest, Rennes, Franc

 

RESEARCH INTERESTS

My research in molecular epidemiology focuses on environmental exposures (e.g. diet and pollutants) and brain aging, with main interests in:

  • Lifestyle (mainly nutritionnal) risk and protective factors  for cognitive decline and dementia
  • Statistical modeling of complex environmental exposures such as multi-nutrient patterns and multi-pollutants networks
  • Exploring the blood exposome (food metabolomics, chemical exposomics…) to identify biomarkers of exposure and biological responses related to brain aging
  • Integrating omics technologies to decipher the biological mechanisms linking environmental exposures to brain health and aging
  • Inter-individual variability in biological responses to dietary exposures, including genetic and microbiota influences

SELECTED PUBLICATIONS

  • Samieri C*, Sonawane A*, Lefèvre-Arbogast S, …Grodstein F, Glass K. Using network science tools to identify novel diet patterns in prodromal dementia: The Three-City Study. Neurology, 2020;94(19):e2014-e2025. doi: 10.1212/WNL.0000000000009399.
  • Lefèvre-Arbogast S, Wagner M, Proust-Lima C, Samieri C. Nutrition and metabolic profiles in the natural history of dementia: recent insights from systems biology and life-course epidemiology. Current Nutrition Reports, 2019;8(3):256-269. doi: 10.1007/s13668-019-00285-1.
  • Low-Yanwen D*, Lefèvre-Arbogast S*, …Samieri C**, Manach C**. Diet-related metabolites associated with cognitive decline revealed by untargeted metabolomics in a prospective cohort. Mol Nutr Food Res, 2019;63(18):e1900177. doi: 10.1002/mnfr.201900177.
  • Lefèvre-Arbogast S, Gaudout D, Bensalem J, …Delcourt C, Samieri C. Pattern of polyphenol intake and the long-term risk of dementia in older persons. Neurology, 2018;90(22):1979-88. doi:10.1212/WNL.0000000000005607.
  • Amadieu C, Lefèvre-Arbogast S, Delcourt C, …Feart C, Samieri C. Nutrient biomarker patterns and long-term risk of dementia in older adults. Alzheimers Dement, 2017;13(10):1125-32. doi:10.1016/j.jalz.2017.01.025.
  • Lefèvre-Arbogast S, Féart C, Dartigues J-F, …Letenneur L, Samieri C. Dietary B Vitamins and a 10-Year Risk of Dementia in Older Persons. Nutrients, 2016;8(12):761. doi:10.3390/nu8120761.
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