Sophie Lefevre-Arbogast

Postdoctoral Research Fellow in Epidemiology, Bordeaux Population Health Research Center, team LEHA, INSERM U1219, Univ Bordeaux

RESEARCH EXPERIENCE

Bordeaux Population Health Research Center (team LEHA) – INSERM U1219 – Univ Bordeaux, Bordeaux, France (Supervision: C. Samieri)
- Since Nov 2019 : Postdoctoral Research Fellow
- Nov 2016 – Oct 2019 : PhD Fellow
- Sept 2016 – Oct 2016 : Biostatistician
- Feb 2016 – Aug 2016 : MSc Training Course

Oct 2019 : Public Health – Epidemiology, PhD, University of Bordeaux, Bordeaux, France
Sept 2016 : Agri-Food Sciences, MSc (French Engineering Degree), Agrocampus Ouest, Rennes, France
Sept 2016 : Applied Statistics, MSc, University of Rennes 2 – Agrocampus Ouest, Rennes, Franc

My research in epidemiology focuses on the food exposome and brain aging, with main interests on:

Nutritional risk and protective factors for cognitive decline and dementia
Statistical modeling of nutritional exposures including multi-nutrient patterns and networks
Molecular epidemiology of diet and brain aging including nutritional metabolomics
Inter-individual variability in biological responses to dietary exposures, including genetic and microbiota influences

Samieri C*, Sonawane A*, Lefèvre-Arbogast S, …Grodstein F, Glass K. Using network science tools to identify novel diet patterns in prodromal dementia: The Three-City Study. Neurology, 2020;94(19):e2014-e2025. doi: 10.1212/WNL.0000000000009399.
Lefèvre-Arbogast S, Wagner M, Proust-Lima C, Samieri C. Nutrition and metabolic profiles in the natural history of dementia: recent insights from systems biology and life-course epidemiology. Current Nutrition Reports, 2019;8(3):256-269. doi: 10.1007/s13668-019-00285-1.
Low-Yanwen D*, Lefèvre-Arbogast S*, …Samieri C**, Manach C**. Diet-related metabolites associated with cognitive decline revealed by untargeted metabolomics in a prospective cohort. Mol Nutr Food Res, 2019;63(18):e1900177. doi: 10.1002/mnfr.201900177.
Lefèvre-Arbogast S, Gaudout D, Bensalem J, …Delcourt C, Samieri C. Pattern of polyphenol intake and the long-term risk of dementia in older persons. Neurology, 2018;90(22):1979-88. doi:10.1212/WNL.0000000000005607.
Amadieu C, Lefèvre-Arbogast S, Delcourt C, …Feart C, Samieri C. Nutrient biomarker patterns and long-term risk of dementia in older adults. Alzheimers Dement, 2017;13(10):1125-32. doi:10.1016/j.jalz.2017.01.025.
Lefèvre-Arbogast S, Féart C, Dartigues J-F, …Letenneur L, Samieri C. Dietary B Vitamins and a 10-Year Risk of Dementia in Older Persons. Nutrients, 2016;8(12):761. doi:10.3390/nu8120761.