
EPICENE
EPIdemiology of Cancer and EnviroNmental Exposures
Pr. Isabelle BALDI, MD, PhD, EPICENE Director
Dr. Alain MONNEREAU, MD, PhD, EPICENE Deputy Director

Details
Université de Bordeaux – ISPED case 11
146 rue Léo-Saignat 33076 BORDEAUX cedex
Objectives
EPICENE’s research is focused on cancers and environmental and occupational determinants of health. Our projects address methodological challenges in a multidisciplinary approach with the aim of expanding knowledge on cancer survival and its determinants, developing new approaches to estimate life-long environmental exposures (Exposome concept), understanding the role of the environment and the occurrence of certain cancers.
Research areas
Theme 1: Cancer survival
Theme 2: Methods in environmental and occupational exposures
Theme 3: Environmental Etiology of Cancer
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Theme 1: Cancer survival: improving knowledge, detecting frail individuals, identifying surrogate endpoints
Although survival rates have improved for the main cancers over the past decades, they remain highly variable depending on the cancer site and on many more individual parameters. We strive to further understand the factors associated with better survival for cancer patients.
Thanks to our involvement in population based cancer registries, we generate new data on cancer survival and its determinants (treatments, comorbidities, care practices, palliative care) for several cancer types (hematological cancers, breast cancer…).We pay particular attention to frail people, for whom efforts of detection and prevention are strongly needed, including elderly people whose number will rapidly increase in the coming decades. We develop new tools for detection programs and we investigate cancer literacy in elderly cancer patients.
Our efforts also focus on improving cancer screening strategies (including organized mass screening). We also develop new biostatistical approaches to assess treatment efficacy and patient survival in randomized controlled trials and in real-life settings
Theme 2: Methods in environmental and occupational exposures: the exposome knowledege
Our research aims to improve the knowledge of levels and determinants of exposure to major contaminants with field measurements in order to identify the main determinants of exposure (usable in retrospective questionnaires and in large population cohorts).
2022 Key Publications
Amadeo B, Penel N, Coindre J-M, Ray-Coquard I, Plouvier S, Delafosse P, et al. Overall and net survival of patients with sarcoma between 2005 and 2010: Results from the French Network of Cancer Registries (FRANCIM). Cancer. 2022;128(13):2483-92.
Baldi I, Lebailly P, Rivollier V. Le fonds d’indemnisation des victimes des pesticides : apports et enjeux. Arch Mal Prof Environ. 2022;83(3):157-8.
Bureau M, Beziat B, Duporte G, Bouchart V, Lecluse Y, Barron E, et al. Pesticide exposure of workers in apple growing in France. Int Arch Occup Environ Health. 2022;95(4):811-23.
Dinart D, Bellera C, Rondeau V. Sample size estimation for cancer randomized trials in the presence of heterogeneous populations. Biometrics. 2022;78(4):1662-73.
Galey L, Albert M, Brossard M, Noel-Suberville C, Garrigou A. Industry 4.0 design project based on exposure situations: A case study in aeronautics. Work. 2022;73(s1):S223-S34.
Gallet J, Laurent F, Paris C, Clin B, Gislard A, Thaon I, et al. Pleural plaques and risk of lung cancer in workers formerly occupationally exposed to asbestos: extension of follow-up. Occup Environ Med. 2022.
Galvin A, Bertrand N, Boulahssass R, De Decker L, Dorval É, Clairaz B, et al. Repenser la prise en charge des sujets âgés atteints d’un cancer : propositions du groupe Priorités Âge Cancer. Bull Cancer. 2022;109(6):714-21.
Renier M, Busson A, Boulanger M, Piel C, Pons R, Tual S, et al. Agricultural exposure and risk of soft tissue sarcomas and gastrointestinal stromal sarcoma in the AGRIculture and CANcer (AGRICAN) cohort. Int J Cancer. 2022;150(150):11.
Villa A, Tremolet K, Martinez B, Petit M, Dascon X, Stanek J, et al. Urine biomonitoring of occupational exposure to methotrexate using a highly sensitive UHPLC-MS/MS method in MRM(3) mode. J Chromatogr B Analyt Technol Biomed Life Sci. 2022;1209:123411.
Poiseuil M, Payet C, Molinie F, Dabakuyo-Yonli TS, Mathoulin-Pelissier S, Amadeo B, et al. Survival after breast cancer according to participation in organised or opportunistic screening and deprivation. Cancer Epidemiol. 2022;82:102312.
Last News


Les chercheurs de l’équipe EPICENE du BPH interviendront au prochain séminaire Vins & environnement du 15 novembre prochain sur la question de la santé en lien avec les utilisations de pesticides en vigne
EventsMembers
AbdessadokHalima
Chargée de projets scientifiques pesticides & santéAlbertMarion
Doctorante en ergonomieAmadeoBrice
Maître de conférencesAudignon-DurandSabyne
Hygiéniste du travail et de l'environnementBaldiIsabelle
BaraultMarion
BelleraCarine
BergeauLydie
BerteaudEmilie
Attachée de recherche cliniqueBouvierGhislaine
BrochardPatrick
BureauMathilde
Chargée de projets scientifiques Pesticides & SantéCanal RaffinMireille
Enseignant-ChercheurCANETJim
Pharmacien ÉpidémiologisteCarlesCamille
MCU-PH en santé travail Equipe EPICENECatherineFrancoise
CONSTANTSabrina
CoureauGaelle
Médecin épidémiologiste MCU-PHCourtinardCoralie
PhD StudentDantasChristel
DarquySylviane
Chercheur Insermde GraafLucie
Post-docDelvaFleur
MD-PhDDepontMarion
DialloKaramoko Alpha
DinartDerek
DubourgCecile
DucampStephane
Hygieniste industriel ; animateur de réseauxDUPEYREMartin
Hygieniste industrielFardeauCeline
FERRARIStéphanie
Attachée de recherche cliniqueGalyCorinne
Attachée de Recherche CliniqueGarrigouAlain
Professeur des universités en ergonomieGauchetBenedicte
GOULARDHELENE
Epidémiologiste - cheffe de projetGoutilleFabienne
GruberAnne
GuilleminLea
Jestin GuyonNolwenn
KoenigPauline
LacourtAude
Chargée de recherche INSERMLe Guyader-PeyrouSandra
LeblancMaylis
Mathoulin-Pelissiersimone
DirectriceMaurelOriane
MenantMorgane
Doctorante en épidémiologieMonnereauAlain
Praticien hospitalier des Centres de Lutte Contre le CancerMorelotSarah
OdanoIsabelle
ORAZIOSébastien
PhDPOISEUILMarie
Post DoctoranteRabetMathilde
Attachée de Recherche CliniqueRaherison Chantal
ProfesseurSeriauMarilene
Souchet RenaudEmma
SwierczynskiGuillaume
TartagliaMarie
DoctoranteTeysseireRaphaelle
TranchetEmeline
VidouFabienne
WOEHRLEHélène
Attachée de recherche clinique