
GHiGS
Global Health in the Global South
Olivier MARCY, MD, PhD, GhiGS director
Renaud BECQUET, PhD, Research Director at Inserm, GhiGS deputy director
Inserm (UMR 1219) – IRD (EMR 271) – Université de Bordeaux (Département Santé Publique)

Details
Université de Bordeaux – ISPED Case 11
146 rue Léo-Saignat
33076 BORDEAUX cedex
Objectives
The objectives of the GHiGS team are:
- to produce data on diseases affecting the global south, their epidemiology, risk factors and consequences;
- to use these findings to design and to evaluate innovative interventions at individual and population level, which are effective, but also equitable and sustainable, and contribute to the advancement of global health.
Per the definition of Koplan et al. (The Lancet 2009;373(9679):1993-5), global health is an area for study, research, and practice that places a priority on improving health and achieving equity in health for all people worldwide. Global health emphasizes transnational health issues, determinants, and solutions; involves many disciplines within and beyond the health sciences and promotes interdisciplinary collaboration; and is a synthesis of population-based prevention with individual-level clinical care.
Per the definition of the World Bank, the global south is made up of Africa, Latin America and the Caribbean, Pacific Islands, and the developing countries in Asia, including the Middle East.
Research areas
Scientific orientations of the research team
The GHiGS team aims to contribute to improving health at individual and population level in countries from the Global South and to contribute to reducing health inequities between countries, as well as within countries.
Low- and middle-income countries, and in particular in Sub-Saharan Africa, are going through major changes including epidemiologic, sociodemographic, economic, agronomic, technological, and climatic transitions. At the same time, they are carrying the triple burden of: (i) infectious diseases, including HIV, tuberculosis, malaria, hepatitis and a number of other emerging infectious disease threats (including hemorrhagic fevers and other epidemics); (ii) growingly prevalent non-communicable diseases (NCDs; diabetes, cancers, hypertension, obesity), and (iii) unprecedented outdoor pollutions and environmental threats. The GHiGS team aims to respond to these major transitions and new challenges through integrated, multi-level and inter-disciplinary research approaches in the context of the Global South.
Among the key highlights of the past five years, the GHiGS team contributed to a major revision in the international HIV treatment guidelines issued by the World Health Organization and was among the rare research teams worldwide having conducted a treatment trial to reduce mortality during the Ebola virus disease epidemic in West Africa.
In the coming years, the GHiGS team will strengthen and expand two key research themes, i.e. infectious diseases and mother and child health issues, to address new challenges in the field of diagnosis, care, and treatment and beyond.
Main publications
- Bernard C, Font H, Diallo Z, Ahonon R, Tine JM, Abouo FN, Tanon A, Messou E, Seydi M, Dabis F, Dartigues JF, de Rekeneire N. Factors associated with verbal fluency in older adults living with HIV in West Africa: A longitudinal study. Trop Med Int Health. 2023 Jan;28(1):35-42. 10.1111/tmi.13830
- Bitty-Anderson AM, Gbeasor-Komlanvi FA, Tchankoni MK, Sadio A, Salou M, Coffie PA, Dagnra CA, Ekouevi DK. HIV prevalence and risk behaviors among female sex workers in Togo in 2017: a cross-sectional national study. Arch Public Health. 2022 Mar 24;80(1):92. 10.1186/s13690-022-00851-0
- Cazes C, Phelan K, Hubert V, Boubacar H, Bozama LI, Sakubu GT, Tshiala BK, Tusuku T, Alitanou R, Kouamé A, Yao C, Gabillard D, Kinda M, Daures M, Augier A, Anglaret X, Shepherd S, Becquet R. Simplifying and optimising the management of uncomplicated acute malnutrition in children aged 6–59 months in the Democratic Republic of the Congo (OptiMA-DRC): a non-inferiority, randomised controlled trial. Lancet Glob Health. 2022 Apr;10(4):e510-e20. 10.1016/s2214-109x(22)00041-9
- Doucet MH, Songbono CT, Plazy M, Martin C, Fritzell C, Sow MS, Traoré FA, Jaspard M, Poda A, Malvy D, Marcy O, Delamou A, Orne-Gliemann J. Perceptions of COVID-19 among communities of Conakry (Guinea): a qualitative study exploring the context of the ANRS COV33 Coverage-Africa therapeutic trial. BMJ Open. 2022 Dec 27;12(12):e061715. 10.1136/bmjopen-2022-061715
- Jaspard M, Mulangu S, Juchet S, Serra B, Dicko I, Lang H-J, Baka BM, Komanda GM, Katsavara JM, Kabuni P, Mambu FM, Isnard M, Vanhecke C, Letord A, Dieye I, Patterson-Lomba O, Mbaya OT, Isekusu F, Mangala D, Biampata JL, Kitenge R, Kinda M, Anglaret X, Muyembe JJ, Kojan R, Ezzedine K, Malvy D. Development of the PREDS score to predict in-hospital mortality of patients with Ebola virus disease under advanced supportive care: Results from the EVISTA cohort in the Democratic Republic of the Congo. EClinicalMedicine. 2022 Dec;54:101699. 10.1016/j.eclinm.2022.101699
- Duvignaud A, Lhomme E, Onaisi R, Sitta R, Gelley A, Chastang J, Piroth L, Binquet C, Dupouy J, Makinson A, Lefevre B, Naccache J-M, Roussillon C, Landman R, Wallet C, Karcher S, Journot V, Nguyen D, Pistone T, Bouchet S, Lafon M-E, Molimard M, Thiebaut R, de Lamballerie X, Joseph J-P, Richert L, Saint-Lary O, Djabarouti S, Wittkop L, Anglaret X, Malvy D. Inhaled ciclesonide for outpatient treatment of COVID-19 in adults at risk of adverse outcomes: a randomised controlled trial (COVERAGE). Clin Microbiol Infect. 2022 Jul;28(7):1010-6. 10.1016/j.cmi.2022.02.031
- Ibrahim Khalil A, Mpunga T, Wei F, Baussano I, de Martel C, Bray F, Stelzle D, Dryden-Peterson S, Jaquet A, Horner MJ, Awolude OA, Trejo MJ, Mudini W, Soliman AS, Sengayi-Muchengeti M, Coghill AE, van Aardt MC, De Vuyst H, Hawes SE, Broutet N, Dalal S, Clifford GM. Age-specific burden of cervical cancer associated with HIV: A global analysis with a focus on sub-Saharan Africa. Int J Cancer. 2022 Mar 1;150(5):761-72. 10.1002/ijc.33841
- Joshi B, Font H, Wobudeya E, Nanfuka M, Kobusingye A, Mwanga-Amumpaire J, Natukunda N, Turyahabwe S, Borand L, Mao TE, Dim B, Ferhi R, Moh R, Kouakou J, Aka Bony R, Breton G, Mustapha A, Matata L, Foray L, Detjen A, Verkuijl S, Sekadde M, Khosa C, Mbassa V, Taguebue JV, Kwedi Nolna S, Bonnet M, Marcy O, Orne-Gliemann J. Knowledge, attitudes and practices on childhood TB among healthcare workers. Int J Tuberc Lung Dis. 2022 Mar 1;26(3):243-51. 10.5588/ijtld.21.0317
- Koladjo BF, Yovo E, Accrombessi M, Agbota G, Atade W, Ladikpo OT, Mehoba M, Degbe A, Jackson N, Massougbodji A, Sossou D, Vianou B, Cot M, Cottrell G, Fievet N, Zeitlin J, Briand V. Malaria in the First Trimester of Pregnancy and Fetal Growth: Results from a Beninese Preconceptional Cohort. J Infect Dis. 2022 May16;225(10):1777-85. 10.1093/infdis/jiac012
- Marcy O, Wobudeya E, Font H, Vessiere A, Chabala C, Khosa C, Taguebue J-V, Moh R, Mwanga-Amumpaire J, Lounnas M, Mulenga V, Mavale S, Chilundo J, Rego D, Nduna B, Shankalala P, Chirwa U, De Lauzanne A, Dim B, Tiogouo Ngouana E, Folquet Amorrissani M, Cisse L, Amon Tanoh Dick F, Komena EA, Kwedi Nolna S, Businge G, Natukunda N, Cumbe S, Mbekeka P, Kim A, Kheang C, Pol S, Maleche-Obimbo E, Seddon JA, Mao TE, Graham SM, Delacourt C, Borand L, Bonnet M. Effect of systematic tuberculosis detection on mortality in young children with severe pneumonia in countries with high incidence of tuberculosis: a stepped-wedge cluster-randomised trial. Lancet Infect Dis. 2022 Nov 14. 10.1016/s1473-3099(22)00668-5
Last News


Publication of the OptiMA clinical trial in eClinicalMedicine concerning the most severely malnourished children
Press
5th Seminar of the Pôle Informatique Mereva from January 25 to 27, 2023, Abidjan, Côte d'Ivoire
Seminars
Renewal of the Franco-Ivorian scientific partnership between the PACCI Program in Abidjan and the GHiGS team in Bordeaux
Events
IPORA (Interdisciplinary Policy-Oriented Research on Africa) agreement signed in Abidjan, Côte d'Ivoire
EventsMembers
AltmannMathias
ChercheurAnglaretXavier
ChercheurArikawaShino
Cheffe de projetBalestreEric
Statistician/data managerBecquetRenaud
Co-Directeur Team GHiGS - Responsable pédagogique du Master Santé InternationaleBernardCharlotte
ChercheuseBeuscartAurelie
Attachée de recherche clinique internationaleBhattaBandana
Cheffe de projetBiayoumouAndré
Responsable administratifBonnetFabrice
ChercheurBriandValérie
M.D., PhD, HDR Chargée de Recherche (IRD)CazesCécile
Cheffe de projetCharpinAurelie
Attachée de recherche clinique internationaleChazallonCorine
StatisticienneClouetGwenaelle
Responsable administratived'ElbeeMarc
Post-doctorate - Health EconomicsDabisFrancois
ChercheurDauresMaguy
Cheffe de projetde CastroNathalie
ChercheuseDoucetMarie-Helene
ChercheuseDuvignaudAlexandre
Maître de Conférences des Universités - Praticien HospitalierEkoueviDidier
ChercheurFritzellCamille
Cheffe de projetGresEmelyne
DoctoranteHabiyambereGemma Guylene
Attachée de recherche clinique internationaleHuyen Ton Nu NguyetMinh
StatisticienneJaquetAntoine
ChercheurJaspardMarie
ChercheuseJOSHIBasant
Post-doc - ChercheurJournotValérie
Ingénieur de recherche - StatisticienneKarcherSophie
Ingénieur Systèmes d'InformationKonuRodion
DoctorantKoskasNicolas
Webmaster BPH Center /Communication manager GHiGSL'hostellierAnthony
Chef de projetLe CarrouJérôme
Systèmes d'informationMachaultVanessa
Cheffe de projetMalatesteKaren
StatisticienneMalvyDenis
Professor of infectious diseasesMarcyOlivier
GHiGS Team Co-Director - MD, MPH, Clinical epidemiologistMesnierSalomé
Attachée de recherche clinique internationaleMontoyoAlice
Cheffe de projetMoreraMaria
Responsable administrativeNguyenDuc
ChercheurNtakpeJean-Baptiste
Chef de projetOrne-GliemannJoanna
Chercheuse en santé publique, Responsable pédagogique Master 2 Santé InternationalePistoneThierry
MD, PhD Senior infectious diseases specialistPlaisyMarie Kerbie
Cheffe de projetPlazyMélanie
Maitre de conférence en Epidémiologie - Santé publique internationalePoublanJulien
Chef de projetRabourdinElodie
Responsable administrativeRoucherClementine
Cheffe de projetTiendrebeogoKiswend Sida Thierry
Chef de projetTouretPierre
Systèmes d'informationVernouxElodie
Gestionnaire administrative et financièreVihoIda
Cheffe de projet