Global Health in the Global South

Olivier MARCY, MD, PhD, GhiGS director
Renaud BECQUET, PhD, Research Director at Inserm, GhiGS deputy director

Inserm (UMR 1219) – IRD (EMR 271) – Université de Bordeaux (Département Santé Publique)


Centre de recherche INSERM U1219
Université de Bordeaux – ISPED Case 11
146 rue Léo-Saignat
33076 BORDEAUX cedex

Tél : 05 57 57 15 80

Tél : 05 57 57 92 40


Gwenaëlle Clouet

Elodie Rabourdin

Olivier Marcy

Dr Olivier Marcy
MD, PhD, GHIGS Director

Olivier Marcy is a clinical epidemiologist and researcher at the University of Bordeaux and research director at IRD (French Institute for Research and Sustainable Development).

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Renaud Becquet

Dr Renaud Becquet
PHD, GHiGS Deputy director

Renaud BECQUET, senior scientist at Inserm, has a PhD and a HDR in epidemiology (University of Bordeaux).

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The objectives of the GHiGS team are:

  • to produce data on diseases affecting the global south, their epidemiology, risk factors and consequences;
  • to use these findings to design and to evaluate innovative interventions at individual and population level, which are effective, but also equitable and sustainable, and contribute to the advancement of global health.

Per the definition of Koplan et al. (The Lancet 2009;373(9679):1993-5), global health is an area for study, research, and practice that places a priority on improving health and achieving equity in health for all people worldwide. Global health emphasizes transnational health issues, determinants, and solutions; involves many disciplines within and beyond the health sciences and promotes interdisciplinary collaboration; and is a synthesis of population-based prevention with individual-level clinical care.

Per the definition of the World Bank, the global south is made up of Africa, Latin America and the Caribbean, Pacific Islands, and the developing countries in Asia, including the Middle East.

Research areas

Scientific orientations of the research team

The GHiGS team aims to contribute to improving health at individual and population level in countries from the Global South and to contribute to reducing health inequities between countries, as well as within countries.

Low- and middle-income countries, and in particular in Sub-Saharan Africa, are going through major changes including epidemiologic, sociodemographic, economic, agronomic, technological, and climatic transitions. At the same time, they are carrying the triple burden of: (i) infectious diseases, including HIV, tuberculosis, malaria, hepatitis and a number of other emerging infectious disease threats (including hemorrhagic fevers and other epidemics); (ii) growingly prevalent non-communicable diseases (NCDs; diabetes, cancers, hypertension, obesity), and (iii) unprecedented outdoor pollutions and environmental threats. The GHiGS team aims to respond to these major transitions and new challenges through integrated, multi-level and inter-disciplinary research approaches in the context of the Global South.

Among the key highlights of the past five years, the GHiGS team contributed to a major revision in the international HIV treatment guidelines issued by the World Health Organization and was among the rare research teams worldwide having conducted a treatment trial to reduce mortality during the Ebola virus disease epidemic in West Africa.

In the coming years, the GHiGS team will strengthen and expand two key research themes, i.e. infectious diseases and mother and child health issues, to address new challenges in the field of diagnosis, care, and treatment and beyond.

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Key Publications 2022

  1. Bernard C, Font H, Diallo Z, Ahonon R, Tine JM, Abouo FN, Tanon A, Messou E, Seydi M, Dabis F, Dartigues JF, de Rekeneire N. Factors associated with verbal fluency in older adults living with HIV in West Africa: A longitudinal study. Trop Med Int Health. 2023 Jan;28(1):35-42. 10.1111/tmi.13830
  2. Bitty-Anderson AM, Gbeasor-Komlanvi FA, Tchankoni MK, Sadio A, Salou M, Coffie PA, Dagnra CA, Ekouevi DK. HIV prevalence and risk behaviors among female sex workers in Togo in 2017: a cross-sectional national study. Arch Public Health. 2022 Mar 24;80(1):92. 10.1186/s13690-022-00851-0
  3. Cazes C, Phelan K, Hubert V, Boubacar H, Bozama LI, Sakubu GT, Tshiala BK, Tusuku T, Alitanou R, Kouamé A, Yao C, Gabillard D, Kinda M, Daures M, Augier A, Anglaret X, Shepherd S, Becquet R. Simplifying and optimising the management of uncomplicated acute malnutrition in children aged 6–59 months in the Democratic Republic of the Congo (OptiMA-DRC): a non-inferiority, randomised controlled trial. Lancet Glob Health. 2022 Apr;10(4):e510-e20. 10.1016/s2214-109x(22)00041-9
  4. Doucet MH, Songbono CT, Plazy M, Martin C, Fritzell C, Sow MS, Traoré FA, Jaspard M, Poda A, Malvy D, Marcy O, Delamou A, Orne-Gliemann J. Perceptions of COVID-19 among communities of Conakry (Guinea): a qualitative study exploring the context of the ANRS COV33 Coverage-Africa therapeutic trial. BMJ Open. 2022 Dec 27;12(12):e061715. 10.1136/bmjopen-2022-061715
  5. Jaspard M, Mulangu S, Juchet S, Serra B, Dicko I, Lang H-J, Baka BM, Komanda GM, Katsavara JM, Kabuni P, Mambu FM, Isnard M, Vanhecke C, Letord A, Dieye I, Patterson-Lomba O, Mbaya OT, Isekusu F, Mangala D, Biampata JL, Kitenge R, Kinda M, Anglaret X, Muyembe JJ, Kojan R, Ezzedine K, Malvy D. Development of the PREDS score to predict in-hospital mortality of patients with Ebola virus disease under advanced supportive care: Results from the EVISTA cohort in the Democratic Republic of the Congo. EClinicalMedicine. 2022 Dec;54:101699. 10.1016/j.eclinm.2022.101699
  6. Duvignaud A, Lhomme E, Onaisi R, Sitta R, Gelley A, Chastang J, Piroth L, Binquet C, Dupouy J, Makinson A, Lefevre B, Naccache J-M, Roussillon C, Landman R, Wallet C, Karcher S, Journot V, Nguyen D, Pistone T, Bouchet S, Lafon M-E, Molimard M, Thiebaut R, de Lamballerie X, Joseph J-P, Richert L, Saint-Lary O, Djabarouti S, Wittkop L, Anglaret X, Malvy D. Inhaled ciclesonide for outpatient treatment of COVID-19 in adults at risk of adverse outcomes: a randomised controlled trial (COVERAGE). Clin Microbiol Infect. 2022 Jul;28(7):1010-6. 10.1016/j.cmi.2022.02.031
  7. Ibrahim Khalil A, Mpunga T, Wei F, Baussano I, de Martel C, Bray F, Stelzle D, Dryden-Peterson S, Jaquet A, Horner MJ, Awolude OA, Trejo MJ, Mudini W, Soliman AS, Sengayi-Muchengeti M, Coghill AE, van Aardt MC, De Vuyst H, Hawes SE, Broutet N, Dalal S, Clifford GM. Age-specific burden of cervical cancer associated with HIV: A global analysis with a focus on sub-Saharan Africa. Int J Cancer. 2022 Mar 1;150(5):761-72. 10.1002/ijc.33841
  8. Joshi B, Font H, Wobudeya E, Nanfuka M, Kobusingye A, Mwanga-Amumpaire J, Natukunda N, Turyahabwe S, Borand L, Mao TE, Dim B, Ferhi R, Moh R, Kouakou J, Aka Bony R, Breton G, Mustapha A, Matata L, Foray L, Detjen A, Verkuijl S, Sekadde M, Khosa C, Mbassa V, Taguebue JV, Kwedi Nolna S, Bonnet M, Marcy O, Orne-Gliemann J. Knowledge, attitudes and practices on childhood TB among healthcare workers. Int J Tuberc Lung Dis. 2022 Mar 1;26(3):243-51. 10.5588/ijtld.21.0317
  9. Koladjo BF, Yovo E, Accrombessi M, Agbota G, Atade W, Ladikpo OT, Mehoba M, Degbe A, Jackson N, Massougbodji A, Sossou D, Vianou B, Cot M, Cottrell G, Fievet N, Zeitlin J, Briand V. Malaria in the First Trimester of Pregnancy and Fetal Growth: Results from a Beninese Preconceptional Cohort. J Infect Dis. 2022 May16;225(10):1777-85. 10.1093/infdis/jiac012
  10. Marcy O, Wobudeya E, Font H, Vessiere A, Chabala C, Khosa C, Taguebue J-V, Moh R, Mwanga-Amumpaire J, Lounnas M, Mulenga V, Mavale S, Chilundo J, Rego D, Nduna B, Shankalala P, Chirwa U, De Lauzanne A, Dim B, Tiogouo Ngouana E, Folquet Amorrissani M, Cisse L, Amon Tanoh Dick F, Komena EA, Kwedi Nolna S, Businge G, Natukunda N, Cumbe S, Mbekeka P, Kim A, Kheang C, Pol S, Maleche-Obimbo E, Seddon JA, Mao TE, Graham SM, Delacourt C, Borand L, Bonnet M. Effect of systematic tuberculosis detection on mortality in young children with severe pneumonia in countries with high incidence of tuberculosis: a stepped-wedge cluster-randomised trial. Lancet Infect Dis. 2022 Nov 14. 10.1016/s1473-3099(22)00668-5
  11. View all of the team’s publications in Oskar

Last News

Posted on : 20 Feb 2024

Bordeaux Summer Schools
Public health, economics, political science
- Africa's populations by 2050

Public health, economics, political science Bordeaux Summer SchoolsAfrica’s populations by 2050 The University of Bordeaux is pleased to announce, within the framework of its Bordeaux Summer Schools, the launch of the following online programme this summer: Africa’s populations by 2050. Taking place from June 24th to June 28th 2024, this online summer school is open […]
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Posted on : 14 Feb 2024

Can nutritional supplementation also improve vaccination coverage?

Can nutritional supplementation also improve vaccination coverage? Does access to nutritional supplements to prevent child malnutrition also improve immunisation coverage among these children in sub-Saharan Africa? Methodological reflections on the study design best suited to the context of humanitarian crises. The GHiGS team (Inserm/IRD/University of Bordeaux) has been working for 8 years now with the […]
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Posted on : 02 Sep 2023

Infectious diseases axis
September 2023 Program

Public Health Seminars INFECTIOUS DISEASES AXIS Program for September Days, Times & location Every FRIDAY from 12h15 to 13h15 Amphi Louis – ISPED Program Friday 08 september 2023 Edouard LHOMME, SISTM, BPH “Immunological aspects of Ebola vaccination” ———— Friday 15 september 2023 Maryline BONNET, IRD, TransVIHMI, Montpellier (invité extérieur) More info “Tuberculosis: toward short treatment […]
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Posted on : 17 Mar 2023

CINEMA & ROUND TABLE EVENING: The factory of pandemics

The BPH Bordeaux Population Health, Isped as part of the events for its 25th anniversary and the Public Health Department of the university, organized in partnership with IRD an evening movie debate: The documentary film “The factory of pandemics” (2022) directed by Marie-Monique Robin with the participation of Juliette Binoche was screened on Wednesday, March […]
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Posted on : 28 Feb 2023

Publication of the OptiMA clinical trial in eClinicalMedicine concerning the most severely malnourished children

Publication of the OptiMA clinical trial in eClinicalMedicine concerning the most severely malnourished children The GHiGS team, in partnership with the humanitarian NGO ALIMA and the National Nutrition Program of the Democratic Republic of Congo (RDC), had implemented a randomized clinical trial in Kasai, DRC, to evaluate a new strategy called “OptiMA,”. In this trial, […]
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Posted on : 07 Feb 2023

5th Seminar of the Pôle Informatique Mereva from January 25 to 27, 2023, Abidjan, Côte d'Ivoire

Les membres du Pôle Informatique Mereva se sont réunis durant trois jours, du 25 au 27 janvier 2023, en Côte d’Ivoire, à l’occasion de leur 5ème Séminaire Informatique, afin d’évaluer collégialement les travaux et activités des années passées, le catalogue de services du Pôle, son mode de communication et de fonctionnement, ses forces et ses […]
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Posted on : 03 Feb 2023

Renewal of the Franco-Ivorian scientific partnership between the PACCI Program in Abidjan and the GHiGS team in Bordeaux

Les Journées Scientifiques du programme de recherche ivoirien PACCI se sont tenues les lundi 23 et mardi 24 janvier 2023 à Abidjan, Côte d’Ivoire, avec pour thème : “Du SIDA aux maladies infectieuses émergentes : la recherche interdisciplinaire avance”. A l’occasion de ces journées, plusieurs institutions françaises et ivoiriennes se sont réunies pour renforcer leur […]
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Posted on : 02 Feb 2023

IPORA (Interdisciplinary Policy-Oriented Research on Africa) agreement signed in Abidjan, Côte d'Ivoire

Le Projet “Interdisciplinary Policy-Oriented Research on Africa” (IPORA) est un des 7 Grands Projets de Recherche (GPR) de l’Université de Bordeaux. L’accord de consortium a été signé ce mardi 24 janvier 2023 à Abidjan, Côte d’Ivoire. Contact : Ida Viho  – Le projet IPORA reunit 4 Universités : l’Université de Bordeaux (France), l’Université Félix Houphouët-Boigny d’Abidjan […]
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