Research projects

The BPH is recognised for its high quality research potential to advance knowledge in the field of public health. The Centre offers a favourable environment through the complementarity of the different research areas and methodologies and the effort to synergise resources.

Research project methodology and implementation:

CIC – 1401 EC:

Clinical investigation centres (CIC) are clinical research infrastructures made available to investigators so that they can conduct their clinical and health research. These projects may aim to achieve better understand of a disease, following up a research idea based on laboratory results, from Inserm for example.

Projects may also be designed to test new treatments. Clinical investigation centres (CIC) are governed by a joint authority, the Department of Hospitalization and Healthcare Organization (DHOS) at the Ministry of Health and Sports, and Inserm. There are several CIC modules including Clinical Epidemiology modules for large-cohort studies.

More information


Provides support for clinical and epidemiological research studies where the hospital (CHU) is an actual or potential sponsor. These projects are designed to be submitted for funding by: PHRC (Hospital Program of Clinical Research ), CHU internal calls for projects, and/or the CHU external funding body (if the CHU is the project sponsor). Since its launch in 2000, it has been part of the clinical investigation center (CIC) plan.


L’UMS 54 MART « Methods and Applied Research for Trials » est une unité mixte de service, portée par l’Inserm et l’université de Bordeaux, créée en septembre 2022. Cette création s’inscrit dans la continuité du CMG-EC qui, depuis 1997, prend officiellement en charge des études promues par l’Inserm-ANRS en tant que centre de méthodologie et de gestion.

More information


(EUropean CLInical trial platform & Development) is an F-CRIN-labeled academic platform, involved in successful collaborations with industry and academia aiming to support the sponsor/investigator duo in implementing clinical trials. EUCLID brings together all the expertise of hospitals, Inserm, and the universities of Bordeaux and Limoges (Coordinators: Prof. Geneviève Chêne, Dr. Laura Richert).

EUCLID provides innovative, tailor-made solutions to cover all the activities required at all stages of clinical development, from protocol design to completion and publication. Located in the heart of a unique scientific environment composed of researchers in biostatistics and epidemiology (Inserm U1219 Centre and U1094 units) and the Institute of Public Health, Epidemiology and Development (ISPED) Euclid meets the highest quality standards by its proactive engagement in the ISO certification process and its certification as an ECRIN Data Management Centre.

The objective of the EUCLID platform is to develop methodological innovations and adequate solutions for optimizing clinical trial design and protocol development , raise funds, obtain regulatory and ethics approvals, manage trial logistics, service contracts for drug management and imaging studies, ensure vigilance, handle data management, perform statistical analyses, and write reports and scientific articles.


Developing statistical models for analysing
complex data (big data, multi-screen models):


The Mereva (Methodology and monitoring of clinical research on HIV and other infectious diseases in developing countries) methodology and management centre (CMG) developed out of the collaboration between Inserm Center 897, University of Bordeaux (UB), the ANRS, and the PACCI programme in Côte d’Ivoire. Most of the Mereva team is based at ISPED on the UB campus and some are based in Abidjan, at the PACCI Programme/ANRS Site. Mereva’s mission is to design and manage clinical studies in developing countries and train young professionals from the North and South in the management of clinical studies.

The Mereva CMG is currently managing the following on-going clinical trials: ANRS 12136 Temprano, ANRS 12206 Monod, ANRS 12269 THILAO, ANRS 12277 Preco-CI, and ANRS 12290 Statis, and preparing the implementation of the following trials: ANRS 12294 FIT2, ANRS 12300 Reflate TB2, and ANRS 12311 TAC. The Mereva CMG collaborates with research teams and centres in Africa (Burkina Faso, Côte d’Ivoire, Guinea, Mali, Mozambique, Senegal, and Togo), Asia (Cambodia and Vietnam), Europe (France and Germany), and South America (Brazil). Mereva is also involved in the coordination and field implementation of the JIKI Phase 2 trial in Guinea, evaluating Favipiravir in the Ebola disease.


The Alzheimer Methodologies Group is a support structure set-up as part of the Alzheimer’s Plan 2008-2012, which has the following missions:

  • Provide methodological advice for clinical and social science studies on Alzheimer’s and related diseases, by informing, guiding and advising project leaders
  • Implement a national platform for clinical research: the Memento cohort

The methodological support activity aims include: contributing to improving the methodological quality of projects and increasing their chances of success in calls for proposals.

The AGMA is the prime owner of the Memento cohort, whose main objective is to improve understanding of the sequence of evolution of Alzheimer’s disease from an early stage and provide a translational research platform open to future national clinical and/or therapeutic research projects. The GMA is part of the CIC-1401 EC Bordeaux (Coordinator: Prof. Geneviève Chêne).