AHeaD

Assessing Health in a Digitalizing Real-World Setting Pharmacoepi & beyond

Details

Centre de recherche INSERM U1219
Université de Bordeaux – ISPED case 11
146 rue Léo-Saignat
33076 BORDEAUX cedex

Tél : 05 57 57 95 12

Antoine Pariente

Pr. Antoine Pariente
MD, PhD, AHeaD Director

Dr. Antoine Pariente did is MD in Pharmacology and Public Health and completed his training with a PhD In Pharmacoepidemiology focussing on population Impact of drugs in dementia.

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Pr. Gayo Diallo
PhD, AHeaD Deputy Director

Gayo Diallo is a full professor in computer science at Bordeaux University (France) since 2022 and is deputy director of the AHeaD research group of the Bordeaux Population Health (BPH) research center (BPH) Inserm-1219.

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Objectives

We are interested in better understanding healthcare real-world setting and better assessing medicines in this observational environment.

In particular, we aim to investigate trajectories of care and their determinants, with a specific interest into emergency care use from one side, and trajectories of care for patients with chronic diseases relating to cardiovascular health or mental health from the other.

Research areas

In the past five years, we belonged to three different teams (“Pharmacoepidemiology – Pharmacoepi”; “Injuries – IETO”; “Informatics in Health – ERIAS”). The collaborations we developed ultimately concentrated most of our teams research efforts, typically around the secondary use of electronic databases for the study of health and medicines in a real-world setting,

Anticipating the research challenges that will emerge from the multiplication, diversification, and complexification of digital health data, we decided to join forces into the AHeaD team project.

This will combine our originating teams expertise in electronic health records databases (HERs), hospital datawarehouses, ontologies, data visualization, knowledge representation, and machine learning and natural language processing for health research, thus constituting a tremendous research opportunity.

Indeed, if the questions and needs for health assessment in real-world settings will remain, how to answer these questions will likely change dramatically. In the coming years, the use of electronic health databases, that developed tremendously over the past 30 years, will need to be complemented using information from other sources that will help strengthen and substantiate the real-world evidence provided. Building bridges between applied health research, already widely using EHRs, and informatics consequently appears as a requirement when envisioning the future development of health-assessment in real-world settings.

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EHDS project and regulatory information
Projet EHDS et informations réglementaires

You will find all the regulatory information (in French) relating to the EHDS project on the link below or in the publication at the bottom of the page /

Vous trouverez toutes les informations réglementaires (en français) relatives au projet EHDS sur le lien ci-dessous ou sur la publication en bas de page

https://www.bordeaux-population-health.center/projet-ehds-notice-information-participants/

 

2023 Key Publications

Allouchery M, Tomowiak C, Singier A, Puyade M, Dari L, Pambrun E, Pariente A, Bezin J, Perault-Pochat M-C, Salvo F. Bleeding risk with concurrent use of anticoagulants and ibrutinib: A population-based nested case-control study. Br J Haematol. 2023;203(2):311-8. https://doi.org/10.1111/bjh.18995

Bezin J, Gouverneur A, Penichon M, Mathieu C, Garrel R, Hillaire-Buys D, Pariente A, Faillie J-L. GLP-1 Receptor Agonists and the Risk of Thyroid Cancer. Diabetes Care. 2023;46(2):384-90. https://doi.org/10.2337/dc22-1148

Boudin M, Diallo G, Drance M, Mougin F. The OREGANO knowledge graph for computational drug repurposing. Sci Data. 2023;10(1):871. https://doi.org/10.1038/s41597-023-02757-0

Chenais G, Gil-Jardiné C, Touchais H, Avalos Fernandez M, Contrand B, Tellier E, Combes X, Bourdois L, Revel P, Lagarde E. Deep Learning Transformer Models for Building a Comprehensive and Real-time Trauma Observatory: Development and Validation Study. JMIR AI. 2023;2:e40843. https://doi.org/10.2196/40843

Chenais G, Lagarde E, Gil-Jardine C. Artificial Intelligence in Emergency Medicine: Viewpoint of Current Applications and Foreseeable Opportunities and Challenges. J Med Internet Res. 2023;25:e40031. https://doi.org/10.2196/40031

Gil-Jardine C, Payen J-F, Bernard R, Bobbia X, Bouzat P, Catoire P, Chauvin A, Claessens Y-E, Douay B, Dubucs X, Galanaud D, Gauss T, Gauvrit J-Y, Geeraerts T, Glize B, Goddet S, Godier A, Le Borgne P, Rousseau G, Sapin V, Velly L, Viglino D, Vigue B, Cuvillon P, Frasca D, Claret P-G. Management of patients suffering from mild traumatic brain injury 2023. Anaesth Crit Care Pain Med. 2023;42(4):101260. https://doi.org/10.1016/j.accpm.2023.101260

Letinier L, Bezin J, Jarne A, Pariente A. Drug-Drug Interactions and the Risk of Emergency Hospitalizations: A Nationwide Population-Based Study. Drug Saf. 2023;46(5):449-56. https://doi.org/10.1007/s40264-023-01283-7

Moal B, Orieux A, Ferte T, Neuraz A, Brat GA, Avillach P, Bonzel C-L, Cai T, Cho K, Cossin S, Griffier R, Hanauer DA, Haverkamp C, Ho Y-L, Hong C, Hutch MR, Klann JG, Le TT, Loh NHW, Luo Y, Makoudjou A, Morris M, Mowery DL, Olson KL, Patel LP, Samayamuthu MJ, Sanz Vidorreta FJ, Schriver ER, Schubert P, Verdy G, Visweswaran S, Wang X, Weber GM, Xia Z, Yuan W, Zhang HG, Zoller D, Kohane IS, (4CE), Boyer A, Jouhet V. Acute respiratory distress syndrome after SARS-CoV-2 infection on young adult population: International observational federated study based on electronic health records through the 4CE consortium. PLoS One. 2023;18(1):e0266985. https://doi.org/10.1371/journal.pone.0266985

Perino J, Demourgues M, Ramaroson H, Bezin J, Micallef J, Miremont-Salame G, Frauger E, Gilleron V, Ong N, Daveluy A. Increase in hospitalisation-associated methadone intoxication in France following first COVID-19 lockdown. Public Health. 2023;223:1-6. https://doi.org/10.1016/j.puhe.2023.07.004

Tournier M, Benard-Laribiere A, Jollant F, Hucteau E, Diop P-Y, Jarne-Munoz A, Pariente A, Oger E, Bezin J. Risk of suicide attempt and suicide associated with benzodiazepine: A nationwide case crossover study. Acta Psychiatr Scand. 2023;148(3):233-41. https://doi.org/10.1111/acps.13582

View all of the team’s publications in Oskar

Last News

Posted on : 02 Feb 2024

Interdisciplinary observatory on digital technologies for surveillance in democracy

News
RIE 2023 The Interdisciplinary observatory on digital technologies for surveillance in democracy co coordinated by Gayo Diallo, deputy director of the BPH AHEAD team have been selected by the University of Bordeaux as interdisciplinary and exploratory research projects. The Observatoire de la surveillance en démocratie aims to monitor and catalogues techniques used by both private […]
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Posted on : 15 Oct 2023

PROJET EHDS
Notice d'information à destination des participants

Focus
PROJET EHDS Espace Européen des Données de Santé NOTICE D’INFORMATION A DESTINATION DES PARTICIPANTS Coordonnées du Responsable scientifique : Gayo DIALLO Laboratoire Bordeaux Population Health Gayo.diallo@u-bordeaux.fr Coordonnées du Délégué à la Protection des Données : Université de Bordeaux DPO 35 place Pey Berland 33000 Bordeaux dpo@u-bordeaux.fr Madame, Monsieur, L’Université de Bordeaux entreprend un projet de […]
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Posted on : 19 Apr 2022

Premier Happy Hour de la recherche en Pharmacie

News
Évènement UFR Sciences Pharmaceutiques – 8 Mars 2022 Afin de faire découvrir aux étudiants en pharmacie la diversité de la recherche dans cette spécialité la première édition du Happy Hour de la Recherche 2022 a été organisée en soirée du 8 mars dernier à l’UFR Odontologie. Maitre de conférences et membre de l’équipe AHEAD du […]
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Members

Al JobooriSamantha

AlloucheryMarion

AmourouxFrancoise

AUGERMuriel

AwukluKokou-Yvon

AzziRabia

Chercheur postdoctoral

BaumevieilleMarie

MCU-HDR

Bénard-LaribièreAnne

PharmD - MSc, Drugs-SafeR

BezinJulien

Maitre de Conférence des Universités - Praticien Hospitalier

BouchetStephane

BoudinMarina

ATER, PhD student

BouyerBenjamin

Researcher - Coordinator of the orthopedic pharmacoepidemiology axis

CatoirePierre

ChenaisGabrielle

PhD graduate student

CombesXavier

ContrandBenjamin

Statisticien / Data Manager

CossinSebastien

Assistant Hospitalier Universitaire

COSTEMarie-Odile

Assistante

Daoud PineauFrederic

DaveluyAmélie

de Germaysibylle

DegondeEmmanuel

DialloGayo

HDR- Professeur en Informatique - Directeur adjoint AHeaD

DiopPapa Yatma

DranceMartin

dugaAlemayehu

DumartinCatherine

MCU-PH, PharmD PhD

EvrardGregoire

GalinskiMichel

GarciaRaphaël

Ingénieur d'études Biostatisticien

GigouVéronique

GoncalvesRuben

GriffierRomain

Médecin de Santé Publique, spécialisé en Informatique Médicale

GriotMarine

GuyonJoris

HucteauEmilie

Ingénieure d'études - Statisticienne

Jarne MunozAna

Ingénieur de recherche

JouhetVianney

LagardeEmmanuel

Directeur équipe IETO

Lerouge BailhacheMarion

LetinierLouis

MATHIEUClément

Postdoctoral researcher

MattaRoula

Mbwe MpohMaurice

MiremontGhada

MolimardMathieu

PU PH Chef du Service de Pharmacologie

MOUGINFleur

Pr in Computer Science

NaprousAlexandre

NoizePernelle

PharmD, PhD

OuedraogoIsmaila

Doctorant

PambrunElodie

Statisticienne

ParienteAntoine

Directeur - Equipe AHeaD, Inserm U1219 BPH

PellayHermine

Post Doctorante en épidémiologie / oncogériatrie

PerinoJustine

PerrierJulia

Doctorante en pharmaco-épidémiologie

PradeauCatherine

QuilesC

RevelPhilippe

RoguesAnne-Marie

Professor MD, PhD, HDR

RussonDylan

SaezTheo

SalmiRachid

MD, PhD

SalvoFrancesco

Senior Researcher - Hospitali Practitioner

SILVA Maria Laura

Maître de Conférences

SingierAllison

PhD Student

SyllaBry

Doctorant

TellierÉric

MD, PhD

Thiao-LayelBruno

Doctorant en informatique et santé

ThiessardFrantz

Tortes St JammesJuiale

TouchaisHélène

TournierM