ACTIVE

Aging, chronic diseases, technology, disability, and environment.

Details

Centre de recherche INSERM U1219
Université de Bordeaux – ISPED
146 rue Léo-Saignat
33076 BORDEAUX cedex

Tél : 05 57 57 15 96

Tél : 05 57 57 15 98

Contact

Marie-Hélène Sage

Pr. Hélène Amieva
PhD, ACTIVE Director

Hélène Amieva has a PhD in Neurosciences. After one year of post-doctoral fellowship at the Psychology Department of Aberdeen University (UK), she has been working in the CNRS as a permanent researcher for 9 years. She is currently Professor of Psychogerontology in Bordeaux University.

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Informations Publications

Objectives

Most of the researches conducted within the ACTIVE team aim at studying:

intrinsic capacities of individuals and environmental factors contributing to develop / maintain/ reduce functional capacity in the context of acute/chronic disease, disability, and/or old age; and
innovative strategies based on the optimization of such factors. The team is composed of epidemiologists, psychologists, cognitive scientists, geriatricians, physical therapists, neurologists and a psychiatrist.

Research area

The first research axis is coordinated by Karine Pérès.
It investigates to what extent intrinsic capacity and environments contribute to develop / maintain / reduce functional ability. Functional trajectories associated with aging process are studied through a continuum distinguishing robustness, pre-frailty, frailty, and activity limitation.
We examine their determinants through a multidimensional approach considering intrinsic capacities (cognition, depression, sensory impairments, personality traits…) and environmental factors (family support, social network, (un)adapted home, professional assistance, digital technologies) that may influence the sequence and speed of functional deterioration.
The heterogeneity of these trajectories is explored in several prospective population-based and clinical studies (PAQUID, AMI, 3C, CONSTANCES, COGLOC…).
More recently, taking advantage of the ongoing cohort studies, the PA-COVID survey, set up very shortly after the first COVID-19 lockdown in France, aims at providing valuable knowledge on older adults’ social and psychological experiences of the COVID-19 crisis and its impact on cognitive, mental and functional health.

The second research axis coordinated by Hélène Sauzéon focuses on innovative strategies based on the optimization of individuals’ intrinsic capacity and/or environments.
As an example of strategies based on optimized environments, the French Alzheimer village is an experimental accommodation facility for older adults with Alzheimer’s disease built like a traditional village.
The team is currently conducting an ambitious multidimensional research program evaluating whether this innovative model is relevant compared to traditional nursing homes (see below). Other researches involve interventions relying on digital technologies.
They generally address two main health issues: rehabilitation access and patient agentivity (i.e., active role of the patient).

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Research area

A research project is being conducted on patients with vascular aphasia to evaluate the benefits of tele-rehabilitation compared to a conventional face-to-face rehabilitation. Another research stresses the role of self-determination in cognitive rehabilitation by leveraging recent technological advances. The program includes a large panel of individuals of various ages and with various disability conditions. The goal is to study the impact of the technology properties of adaptability (self-configuration of objectives/ contents of the intervention by the care recipient) and/or adaptivity (self-configuration of intervention by machine learning algorithms) on rehabilitation results.

2024 Key publications

Boucaud-Maitre D, Letenneur L, Dartigues JF, Amieva H, Tabue-Teguo M. Letter to the Editor: The French Model of Senior Housing to Tackle Housing Inequalities. J Frailty Aging. 2024;13(1):73. https://doi.org/10.14283/jfa.2024.7

Boucaud-Maitre D, Villeneuve R, Rambhojan C, Simo-Tabue N, Thibault N, Rinaldo L, Dartigues J-F, Drame M, Amieva H, Tabue-Teguo M. Clinical Characteristics of Older Adults Living in Foster Families in the French West Indies: Baseline Screening of the KArukera Study of Aging in Foster Families (KASAF) Cohort. Innov Aging. 2024;8(7):igae063. https://doi.org/10.1093/geroni/igae063

Caillot-Ranjeva S, Bergua V, Meillon C, Amieva H. Impact of Cohabitation during Confinement on Older Adults’ Negative Affect: What Specificity of Life as a Couple? J Frailty Aging. 2024;13(1):64-70. https://doi.org/10.14283/jfa.2023.25

Dorey J-M, Pongan E, Padovan C, Chaillet A, Herrmann M, Krolak-Salmon P, Rouch I. Prodromal or mild Alzheimer’s disease: Influence of neuropsychiatric symptoms and premordid personality on caregivers’ burden. Int J Geriatr Psychiatry. 2024;39(6):e6114. https://doi.org/10.1002/gps.6114

Gbessemehlan A, Cambois E, Brouard N, Letenneur L, Amieva H, Peres K. Differences between subjective and disability health expectancies across ages in older adults. Sci Rep. 2024;14(1):14731. https://doi.org/10.1038/s41598-024-65416-3

Goncalves S, Mandigout S, Le Bourvellec M, Duclos NC. Comparison of motion sensor and heart rate monitor for assessment of physical activity intensity in stroke outpatient rehabilitation sessions: an observational study. J Rehabil Med. 2024;56:jrm40559. https://doi.org/10.2340/jrm.v56.40559

Hernandez-Ruiz V, Roubaud-Baudron C, Von Campe H, Retuerto N, Megraud F, Helmer C, Amieva H, Peres K. Association between Helicobacter pylori infection and incident risk of dementia: The AMI cohort. J Am Geriatr Soc. 2024;72(4):1191-8. https://doi.org/10.1111/jgs.18748

Husky MM, Pic O, Callahan S, Navarro-Mateu F. Twelve-month suicidal ideation, incidence and persistence among college students pre-pandemic and during the pandemic: A longitudinal study. Psychiatry Res. 2024;331:115669. https://doi.org/10.1016/j.psychres.2023.115669

Ruiz-Manriquez CA, Avila-Funes JA, Branas F, Crabtree-Ramirez B, Amieva H, Hernandez-Ruiz V. Association between a lower T-CD4+ /CD8+ lymphocyte ratio and cognitive impairment in older persons with HIV. Eur Geriatr Med. 2024. https://doi.org/10.1007/s41999-024-01079-7

Saulnier T, Fabbri M, Le Goff M, Helmer C, Pavy-Le Traon A, Meissner WG, Rascol O, Proust-Lima C*, Foubert-Samier A*. Patient-perceived progression in multiple system atrophy: natural history of quality of life. J Neurol Neurosurg Psychiatry. 2024;95(9):804-11. https://doi.org/10.1136/jnnp-2023-332733

* equal contribution

View all of the team’s publications in Oskar

Last News

Posted on : 20 May 2025

HDR Defense : Noémie DUCLOS

Events

Noémie DUCLOS will present her defence HDR in public health (French post-doctoral degree allowing its holder to supervise PhD students)” entitled : “Vers une approche écologique de la mobilité : intégrer les dimensions incarnée, située , étendue et émergente pour soutenir la participation en environnement ordinaire” The defense (in french […]

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Posted on : 22 Apr 2025

Public Health Seminars : DEVELOPMENT OF A TRAINING APPROACH FOR THE USE OF MOTORISED WHEELCHAIRS FOR PEOPLE WITH COGNITIVE DISABILITIES

Seminars

Next public health seminar will be held on : DEVELOPMENT OF A TRAINING APPROACH FOR THE USE OF MOTORISED WHEELCHAIRS FOR PEOPLE WITH COGNITIVE DISABILITIES Speaker : Alice PELLICHERO Maîtresse de conférences associée (ergothérapeute PhD, Université de bordeaux Institut Universitaire des Sciences de la Réadaptation Equipe ACTIVE – BPH, INSERM U1219 […]

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Posted on : 18 Oct 2024

Installation ceremony of the senior members of the Institut Universitaire de France

Awards

On Friday, October 18, 2024, the installation ceremony for the new members of the French University Institute (IUF) took place in the Grand Amphitheater of the Sorbonne, in the presence of Mr. Patrick Hetzel, Minister of Higher Education and Research. The winners, known as IUF members, are professors and researchers selected by […]

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Posted on : 10 Oct 2024

10th and 11th of October took place the Annual Days of the PPR Autonomie

Events

Last 10th and 11th of October took place the Annual Days of the PPR Autonomie. These days aimed to reinforce the community of researchers and stakeholders working on autonomy, and to present the winning projects of the PPR. The ACTIVE team has the chance to be involved in 2 consortia: The […]

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Posted on : 18 Sep 2024

Virgilio Hernandez-Ruiz joined the Lancet Commission on "HIV and Aging"

Team

Virgilio Hernandez-Ruiz joined the Lancet Commission on “HIV and Aging This Commission relies on a working group composed of international experts in medicine, public health, geriatrics, epidemiology, and social sciences, aiming at analyzing the medical, social, and economic challenges posed by the aging of people living with HIV in order to promote appropriate […]

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Posted on : 18 Sep 2024

Research stay of Helen Maria Vasiliadis from the University of Sherbrooke: Epidemiological Approach of mental health across different life stages

Team

As part of the “Visiting Scholars” program, Helen Maria Vasiliadis, Professor of epidemiology at the University of Sherbrooke (Canada), got support from the University of Bordeaux for a two-month research stay. She gave lectures within the ACTIVE team, the BPH center, and the Faculty of Psychology, on epidemiological approach […]

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Posted on : 05 Jul 2024

ACTIVE Team General Assembly 2024

Events

The ACTIVE team held its General Assembly last July 5th, an opportunity, as every year, to review the ongoing projects of the team and discuss some future prospects in a friendly atmosphere.

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Posted on : 11 Jun 2024

Hélène AMIEVA
laureate of the 2024 selection of the Institut Universitaire de France (IUF)

Awards

Hélène AMIEVA lauréate de la sélection 2024 de l’Institut universitaire de France IUF The BPH is proud to announce that Hélène AMIEVA, researcher and director of the ACTIVE team, is a laureate of the 2024 selection of the Institut Universitaire de France (IUF) in the category of fundamental chair, starting from October 1, 2024, for […]

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Posted on : 18 Dec 2023

ACTIVE Ph.D students in the spotlights

News

ACTIVE Ph.D students in the spotlights Thesis defenses in 2023: Marion PECH defended her PhD thesis in Psychology on March 17 (title: Detection of risky situations in daily life among frail elderly people using artificial intelligence methods: testing of a device in the general population) supervised by Helene Amieva & Jenny Benois-Pineau. Sophie ARHEIX-PARRAS defended […]

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Posted on : 25 Oct 2023

General Assembly of the ACTIVE team

Events

General Assembly of the ACTIVE team The ACTIVE team held its General Assembly on October 23 and 24. On the program, discussion about achievements and prospects, and above all, the opportunity for the whole team to be together in a stimulating and friendly atmosphere.

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Posted on : 05 Oct 2023

The ACTIVE team celebrates the Village Landais Alzheimer Henri Emmanuelli annual festival

Events

The ACTIVE team celebrates the Village Landais AlzheimerHenri Emmanuelli annual festival Since its opening in 2020, the ACTIVE team is conducting an evaluation of the Village Landais Henri Emmanuelli (Alzheimer Village), an innovative and experimental dementia friendly-facility, unique in France. The study involves a prospective follow up of the villagers, family caregivers and healthcare professionals […]

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Posted on : 10 Sep 2023

Linking the European Alzheimer Villages: The ACTIVE team meets the Italian Alzheimer Village

Focus

Linking the European Alzheimer Villages:The ACTIVE team meets the Italian Alzheimer Village Since its opening in 2020, the ACTIVE team is conducting an evaluation of the Village Landais Henri Emmanuelli (Alzheimer Village), an innovative and experimental dementia friendly-facility, unique in France. The study involves a prospective follow up of the villagers, family caregivers and healthcare […]

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Posted on : 10 Apr 2023

Invitation of Prof Sylvie Nadeau, physiotherapist at the Readaptation School of Montreal University

Seminars

Invitation of Prof Sylvie Nadeau,physiotherapist at the Readaptation School of Montreal University Prof Sylvie Nadeau is full professor in physiotherapy teaching at the Readaptation School of Montreal University, and researcher at the Centre de Recherche Interdisciplinaire en Réadaptation (CRIR) and at the Institut universitaire sur la réadaptation en déficience physique de Montréal (IURDPM). Prof Sylvie […]

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Posted on : 20 Apr 2022

Les têtes au football

Press

Une équipe de recherche française publie une série de données inédites sur une pratique pas si anodine pour la santé des joueurs. Le Docteur Hélène Cassoudesalle et le Professeur Patrick Dehail, deux médecins hospitalo-universitaires au CHU et à l’université de Bordeaux et membres de l’équipe Inserm ACTIVE du centre de recherche Bordeaux Population Health […]

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