PhD student in epidemiology

Constance Bordes obtained a master’s degree in Public Health/Epidemiology from the Institute of Public Health, Epidemiology and Development (ISPED) in Bordeaux (2019). Constance joined ELEANOR team during her master’s internship, where she explored the mechanisms of early MRI-markers of cerebral Small Vessel Disease. Between 2019 and 2021, Constance worked in Pr. Debette team as an epidemiologist. Her research interests are focus on exploring the very early mechanisms of structural brain changes leading to cognitive decline or dementia as well as the mechanisms underlying the association between Small Vessel Disease and cognitive decline/dementia. 

She is currently a PhD student in epidemiology under the supervision of Pr. Debette with the purpose of exploring the lifetime impact of cerebral small vessel disease on cognitive decline and dementia, by using genomics as a tool.


– Sargurupremraj M, Suzuki, H, Jian, X, (…) Bordes C, (…) Debette S. Cerebral small vessel disease genomics and its implications across the lifespan, Nat Commun, 2020. (doi: 10.1038/s41467-020-19111-2)

– Soumaré A, Beguedou N, (..) Bordes C,  Tzourio C, Mazoyer B, Debette S. Prevalence, severity, and clinical management of brain incidental findings in healthy young adults: MRi-Share cross-sectional study, Front Neurol, 2021. (doi: 10.3389/fneur.2021.675244)

Bordes C, Sargurupremraj M, Mishra A, Debette S. Genetics of common cerebral small vessel disease, Nat Neurol Rev, 2022. (doi: 10.1038/s41582-021-00592-8)

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