The PHARes Team aims to improve our understanding of and act upon the greatest risks and threats to population health, representing a large share of morbidity and mortality as well as social determinants of health and healthcare expenditure.
Through this translational approach, We seek to reduce, the impact of these risks and treats (taking into account social and environmental inequalities, including inequalities in access to healthcare) by:
. Improving risks factors and inequalities measurement with real-world data and methods developed for and applied to observational studies and thus providing the evidence based for a critical building block for action,
. Developing innovative methods (observational and experimental) for the development and evaluation of complex population health interventions,
. Analysing of social and political processes underlying the unequal distribution of risks and health inequities in order to influence decision-making.
The team works on five topics
1. Methods for population health intervention research (Linda Cambon)
This topic involves conducting research on research (meta-research) on concepts and methods for the evaluation of prevention and health promotion interventions. The questions cover all stages of the approach, from the development to the scaling up of an intervention,
2. Social determinants, migrations dynamics, environment & health (Stéphanie Vandentorren, Laurence Kotobi)
This research theme relies on a strong interdisciplinary convergence on the cross-cutting themes of social inequalities, deprived populations, environmental risks and their relation to population health and health inequalities. Our research questions address the following issues:
– Social determinants of maternal, child, sexual & reproductive health among vulnerable populations
– Health status and healthcare access of vulnerable populations.
– Innovative approaches to advance health and health equity in decision-making processes at territorial level.
3. Pathways and determinants of health (Florence Saillour)
The concept of pathway has been developed to respond to the need to make our health system and society evolve in the face of the increase in life expectancy, of the number of patients with chronic illnesses and of the complexity of managements. The identification of interventions to improve pathways and reduce inequalities in access to care is another important issue, leading to significant improvements in population health. therefore focusing on three main goals :
– Characterization of pathways
– Identification of determinants of health
– Optimisation of care pathways and reduction of health inequalities,
4. Innovations for prevention in healthcare system (François Alla)
The growing prevalence of chronic diseases is a major challenge for the sustainability of health systems. There is a need to transform health systems by increasing prevention and by implementing innovative organisations in management of these diseases. This transformation will require the development and the analysis of research- and field-based interventions. Health system transformation also requires transferring innovative models into public decisions and practices, and requires these actions to occur across health systems.The objective of this theme is to identify, develop and/or evaluate technological (such as mobile health in prevention strategies) and organisational innovations (such as interprofessional collaboration to improve professional practice and health-care outcomes) that fall within the scope of prevention in the health care system (or « preventive clinical practices »), in hospital or outpatient healthcare. Research covers all stages of innovation, from development to scale-up.
5. Economics and management of healthcare organizations (Jérôme Wittwer)
Our aim is to conduct research projects that evaluate health policies and health interventions using an applied and multidisciplinary approach, involving economists, management researchers, health professionals (doctors and nurses) and other social science researchers with expertise in health services research. This research addresses questions related to the evaluation of health systems and policies from a variety of perspectives depending on the object studied (healthcare utilization, healthcare pathways, technological or organizational innovations …), the relevant evaluation outcome (take-up of public programs, efficiency, healthcare access inequalities, staff turnover, rehospitalization …), the available data and the appropriate methods (econometrics using administrative data, experimental studies, medico economic modelling of clinical data and registry data, qualitative interviews…).
Cambon L, Alla F. Understanding the complexity of population health interventions: assessing intervention system theory (ISyT). Health Res Policy Syst. 2021 Jun 19;19(1):95. https://doi.org/10.1186/s12961-021-00743-9
Chamberlain JD, Rouanet A, Dubois B, Pasquier F, Hanon O, Gabelle A, Ceccaldi M, Krolak-Salmon P, Bejot Y, Godefroy O, Wallon D, Gentric A, Chene G, Dufouil C, Memento Study g. Investigating the association between cancer and the risk of dementia: Results from the Memento cohort. Alzheimers Dement. 2021 Sep;17(9):1415-21. https://doi.org/10.1002/alz.12308
Frison E, Proust-Lima C, Mangin JF, Habert MO, Bombois S, Ousset PJ, Pasquier F, Hanon O, Paquet C, Gabelle A, Ceccaldi M, Annweiler C, Krolak-Salmon P, Bejot Y, Belin C, Wallon D, Sauvee M, Beaufils E, Bourdel-Marchasson I, Jalenques I, Chupin M, Chene G, Dufouil C, Group MCS. Diabetes Mellitus and Cognition: Pathway Analysis in the MEMENTO Cohort. Neurology. 2021 Aug 24;97(8):e836-e48. https://doi.org/10.1212/wnl.0000000000012440
Martin-Fernandez J, Aromatario O, Prigent O, Porcherie M, Ridde V, Cambon L. Evaluation of a knowledge translation strategy to improve policymaking and practices in health promotion and disease prevention setting in French regions: TC-REG, a realist study. BMJ Open. 2021 Sep 30;11(9):e045936. https://doi.org/10.1136/bmjopen-2020-045936
Schwarzinger M, Watson V, Arwidson P, Alla F, Luchini S. COVID-19 vaccine hesitancy in a representative working-age population in France: a survey experiment based on vaccine characteristics. Lancet Public Health. 2021 Apr;6(4):e210-e21. https://doi.org/10.1016/S2468-2667(21)00012-8
Cambon L, Schwarzinger M, Alla F. Increasing acceptance of a vaccination program for coronavirus disease 2019 in France: A challenge for one of the world’s most vaccine-hesitant countries. Vaccine. 2022 Jan 21;40(2):178-82. https://doi.org/10.1016/j.vaccine.2021.11.023
Caumette E, Di Meglio A, Vaz-Luis I, Charles C, Havas J, de Azua GR, Martin E, Vanlemmens L, Delaloge S, Everhard S, Martin A-L, Merimeche AD, Rigal O, Coutant C, Fournier M, Jouannaud C, Soulie P, Cottu P-H, Tredan O, Menvielle G, Dumas A. Change in the value of work after breast cancer: evidence from a prospective cohort. J Cancer Surviv. 2022 Mar 10. https://doi.org/10.1007/s11764-022-01197-w
Motreff Y, Pirard P, Vuillermoz C, Rabet G, Petitclerc M, Stene LE, Baubet T, Chauvin P, Vandentorren S. Mental health care utilization by first responders after Paris attacks. Occup Med (Lond). 2022 Feb 22;72(2):81-90. https://doi.org/10.1093/occmed/kqab150
Centre de recherche INSERM U1219
Université de Bordeaux, ISPED case 11
146 rue Léo-Saignat
33076 BORDEAUX cedex
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