EPICENE

EPIdemiology of Cancer and EnviroNmental Exposures

Pr. Isabelle BALDI, MD, PhD, EPICENE Director
Dr. Alain MONNEREAU, MD, PhD, EPICENE Deputy Director

Details

Centre de recherche INSERM U1219
Université de Bordeaux – ISPED case 11
146 rue Léo-Saignat 33076 BORDEAUX cedex

Tél : 05 57 57 95 31

Tél : 05 57 57 12 34

Fax : 05 57 57 47 33

Contact

Sabrina Constant

Christel Dantas

Isabelle Baldy

Pr. Isabelle Baldi
MD, PhD, EPICENE Director

Isabelle Baldi is the head of the EPICENE team of the BPH INSERM center (INSERM U1219).

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Dr. Fleur Delva
MD, PhD, EPICENE Deputy director

Fleur Delva  is a medical doctor specialized in public health and hospital practitioner at the Bordeaux University Hospital and co-director of the INSERM EPICENE “Cancer environment” team.

 

 

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Objectives

EPICENE’s research is focused on cancers and environmental and occupational determinants of health. Our projects address methodological challenges in a multidisciplinary approach with the aim of expanding knowledge on cancer survival and its determinants, developing new approaches to estimate life-long environmental exposures (Exposome concept), understanding the role of the environment and the occurrence of certain cancers.

Research areas

Theme 1: Cancer survival
Theme 2: Methods in environmental and occupational exposures
Theme 3: Environmental Etiology of Cancer

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Theme 1: Cancer survival: improving knowledge, detecting frail individuals, identifying surrogate endpoints

Although survival rates have improved for the main cancers over the past decades, they remain highly variable depending on the cancer site and on many more individual parameters. We strive to further understand the factors associated with better survival for cancer patients.

Thanks to our involvement in population based cancer registries, we generate new data on cancer survival and its determinants (treatments, comorbidities, care practices, palliative care) for several cancer types (hematological cancers, breast cancer…).We pay particular attention to frail people, for whom efforts of detection and prevention are strongly needed, including elderly people whose number will rapidly increase in the coming decades. We develop new tools for detection programs and we investigate cancer literacy in elderly cancer patients.

Our efforts also focus on improving cancer screening strategies (including organized mass screening). We also develop new biostatistical approaches to assess treatment efficacy and patient survival in randomized controlled trials and in real-life settings

Theme 2: Methods in environmental and occupational exposures: the exposome knowledege

Our research aims to improve the knowledge of levels and determinants of exposure to major contaminants with field measurements in order to identify the main determinants of exposure (usable in retrospective questionnaires and in large population cohorts).

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2023 Key Publications

Audignon-Durand S, Ramalho O, Mandin C, Roudil A, Le Bihan O, Delva F, Lacourt A. Indoor exposure to ultrafine particles related to domestic activities: A systematic review and meta-analysis. Sci Total Environ. 2023;904:166947. https://doi.org/10.1016/j.scitotenv.2023.166947

Courtinard C, Gourgou S, Jacot W, Carton M, Guerin O, Vacher L, Bertaut A, Le Deley M-C, Perol D, Marino P, Levy C, Uwer L, Perrocheau G, Schiappa R, Bachelot F, Parent D, Breton M, Petit T, Filleron T, Loeb A, Pelissier SM, Robain M, Delaloge S, Bellera C. Association between progression-free survival and overall survival in women receiving first-line treatment for metastatic breast cancer: evidence from the ESME real-world database. BMC Med. 2023;21(1):87. https://doi.org/10.1186/s12916-023-02754-5

Duchange N, Poiseuil M, Rollet Q, Piette C, Cosson M, Quertier M-C, Moutel G, Darquy S. How do women comply with cancer screenings? A study in four regions of France. BMC Womens Health. 2023;23(1):190. https://doi.org/10.1186/s12905-023-02311-5

Frasca M, Jonveaux T, Lhuaire Q, Bidegain-Sabas A, Chanteclair A, Francis-Oliviero F, Burucoa B. Sedation practices in palliative care services across France: a nationwide point-prevalence analysis. BMJ Support Palliat Care. 2023;13(e3):e1326-34. https://doi.org/10.1136/spcare-2023-004261

Galvin A, Amadeo B, Frasca M, Soubeyran P, Rondeau V, Delva F, Peres K, Coureau G, Helmer C, Mathoulin-Pelissier S. Association between pre-diagnosis geriatric syndromes and overall survival in older adults with cancer (the INCAPAC study). J Geriatr Oncol. 2023;14(6):101539. https://doi.org/10.1016/j.jgo.2023.101539

Kim J, Leon ME, Schinasi LH, Baldi I, Lebailly P, Freeman LEB, Nordby K-C, Ferro G, Monnereau A, Brouwer M, Kjaerheim K, Hofmann JN, Straif K, Kromhout H, Schuz J, Togawa K. Exposure to pesticides and risk of Hodgkin lymphoma in an international consortium of agricultural cohorts (AGRICOH). Cancer Causes Control. 2023;34(11):995-1003. https://doi.org/10.1007/s10552-023-01748-1

Poiseuil M, Payet C, Molinie F, Dabakuyo-Yonli TS, Mathoulin-Pelissier S, Amadeo B, Coureau G. Survival after breast cancer according to participation in organised or opportunistic screening and deprivation. Cancer Epidemiol. 2023;82:102312. https://doi.org/10.1016/j.canep.2022.102312

Silva V, Gai L, Harkes P, Tan G, Ritsema CJ, Alcon F, Contreras J, Abrantes N, Campos I, Baldi I, Bureau M, Christ F, Mandrioli D, Sgargi D, Paskovic I, Polic Paskovic M, Glavan M, Hofman J, Huerta Lwanga E, Norgaard T, Bilkova Z, Osman R, Khurshid C, Navarro I, de la Torre A, Sanz P, Angeles Martinez M, Dias J, Mol H, Gort G, Martins Figueiredo D, Scheepers PTJ, Schlunssen V, Vested A, Alaoui A, Geissen V. Pesticide residues with hazard classifications relevant to non-target species including humans are omnipresent in the environment and farmer residences. Environ Int. 2023;181:108280. https://doi.org/10.1016/j.envint.2023.108280

Teysseire R, Barron E, Baldi I, Bedos C, Chazeaubeny A, Le Menach K, Roudil A, Budzinski H, Delva F. Pesticide Exposure of Residents Living in Wine Regions: Protocol and First Results of the Pestiprev Study. Int J Environ Res Public Health. 2023;20(5):3882 https://doi.org/10.3390/ijerph20053882

Villa A, Geshkovska A, Bellagamba G, Baldi I, Molimard M, Verdun-Esquer C, Lehucher-Michel M-P, Canal-Raffin M. Factors associated with internal contamination of nurses by antineoplastic drugs based on biomonitoring data from a previous study. Int J Hyg Environ Health. 2023;254:114264. https://doi.org/10.1016/j.ijheh.2023.114264

View all of the team’s publications in Oskar

Last News

Posted on : 24 May 2023

PUBLICATIONS: 2 publications studying women's participation in screening for three cancers have just been published by researchers from the Epicene team

Press
Two publications studying women’s participation in screening for cancers have just been published by researchers from the Epicene team From the age of 50, a French woman is invited to participate in 3 organized cancer screenings (breast, colorectal, cervical*). What are their behaviors and possible explanations for non-participation? A questionnaire was proposed to women aged […]
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Posted on : 10 Nov 2022

Les chercheurs de l’équipe EPICENE du BPH interviendront au prochain séminaire Vins & environnement du 15 novembre prochain sur la question de la santé en lien avec les utilisations de pesticides en vigne

Events
Ce 6ème séminaire Vins & environnement organisé par l’ISVV Institut des Sciences de la Vigne et du Vin de l’Université de Bordeaux, en partenariat avec INNO’VIN le cluster de la filière vitivinicole en Nouvelle-Aquitaine portera sur « Viticulture, pesticides et santé : Que récolte la recherche ? » Contact : Isabelle.baldi@u-bordeaux.fr Mathilde Bureau@u-bordeaux.fr Le séminaire […]
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Members

AbdessadokHalima

Chargée de projets scientifiques pesticides & santé

AlbertMarion

Doctorante en ergonomie

AmadeoBrice

Maître de conférences

Audignon-DurandSabyne

PhD

BaldiIsabelle

BaraultMarion

BelleraCarine

BergeauLydie

BerteaudEmilie

Attachée de recherche clinique

BouvierGhislaine

BrochardPatrick

BureauMathilde

Chargée de projets scientifiques Pesticides & Santé

Canal RaffinMireille

Enseignant-Chercheur

CANETJim

Pharmacien Épidémiologiste

CarlesCamille

MCU-PH en santé travail Equipe EPICENE

CatherineFrancoise

CONSTANTSabrina

CoureauGaelle

Médecin épidémiologiste MCU-PH

CourtinardCoralie

PhD Student

DantasChristel

DarquySylviane

Chercheur Inserm

de GraafLucie

Post-doc

DelvaFleur

MD-PhD

DepontMarion

DialloKaramoko Alpha

DinartDerek

DubourgCecile

DucampStephane

Hygieniste industriel ; animateur de réseaux

DUPEYREMartin

Hygieniste industriel

FardeauCeline

FERRARIStéphanie

Attachée de recherche clinique

GalyCorinne

Attachée de Recherche Clinique

GarrigouAlain

Professeur des universités en ergonomie

GauchetBenedicte

GOULARDHELENE

Epidémiologiste - cheffe de projet

GoutilleFabienne

GruberAnne

GuilleminLea

Jestin GuyonNolwenn

KoenigPauline

LacourtAude

Chargée de recherche INSERM

Le Guyader-PeyrouSandra

LeblancMaylis

Mathoulin-Pelissiersimone

Directrice

MaurelOriane

MenantMorgane

Doctorante en épidémiologie

MonnereauAlain

Praticien hospitalier des Centres de Lutte Contre le Cancer

MorelotSarah

OdanoIsabelle

ORAZIOSébastien

PhD

POISEUILMarie

Post Doctorante

RabetMathilde

Attachée de Recherche Clinique

Raherison Chantal

Professeur

SeriauMarilene

Souchet RenaudEmma

SwierczynskiGuillaume

TartagliaMarie

Doctorante

TeysseireRaphaelle

TranchetEmeline

VidouFabienne

WOEHRLEHélène

Attachée de recherche clinique