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Two BPH researchers obtain their HDR: Boris Hejblum and Mélanie Prague

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Boris Hejblum and Melanie Prague from the BPH’s SISTM team recently obtained their Habilitation to Supervise Research (HDR).
This is the ultimate presentation for a researcher and validates his or her ability to supervise doctoral students.
This recognition marks a key stage in the careers of our two researchers

 

 

 

 

 

 

Mélanie Prague defended her HDR on “Mechanistic and statistical models for the treatment and control of infectious diseases“.
Her work details the development of mechanistic models, their application to intra-host viral dynamics, and population-level interventions against epidemics, targeting diseases such as HIV, Ebola, and SARS-CoV-2.

This HDR was an opportunity for her to take a look back at her career, but also to structure her research and ideas at the interface between mechanistic and statistical modelling, applied to infectious diseases… by writing part of her work, under the sun of Saint-Martin.

As well as being a rigorous scientific exercise, the presentation provided an opportunity for a stimulating exchange with the jury. In the end, this exercise enabled Mélanie to define the major questions to be explored in the years to come.

 

 

 

Boris Hejblum defended his HDR entitled: “Statistical methods for leveraging high-dimensional data from high-throughput measurements in vaccine clinical development”.
His research career at the intersection of biostatistics, public health, and immunology, between France and the United States, has led him to address the specific methodological challenges of analyzing high-dimensional longitudinal biomedical data, particularly in the study of infectious diseases and the development of new vaccines.
His work focuses on developing innovative statistical methods to analyze large-scale, multidimensional data, notably from gene expression and from flow cytometry measurements, which are frequently collected in early-phase vaccine trials. These approaches aim to better characterize immune responses, thereby accelerating both the design and evaluation of future vaccines.

Congratulations to our two researchers for this important step in their careers.



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