HEALTHY
Epidemiology, development and prevention of mental health problems using a life span perspective

Details
Université de Bordeaux, ISPED case 11
146 rue Léo-Saignat 33076 BORDEAUX cedex
Objectives
The research focus of our team is to understand and prevent mental health problems in youths.
We aim to:
- Investigate the risk and protective factors of Mental, Neurological and Substance use (MNS) problems in young people using a lifespan perspective
- Test the efficacy of strategies to prevent Mental, Neurological and Substance use problems and build resilience to stressors in youths / parents
Research areas
In the past five years the team has provided relevant evidences on the early contribution of the social environment and biological factors on youth mental health (cognition, externalizing behaviors, internalizing problems, ADHD and risk for suicide).
Team members have studied the modulation of biological factors by the social environment in relation to externalizing problems and ADHD and the relative contributions of genes and environment on the developmental course of the ADHD phenotype and suicide risk, from the peri-conceptional period to adolescence. Team members have also found that cytokine patterns in the cord blood is associated with childhood anxiety/depression symptoms.
Regarding interventions aiming at improving mental health, cognitive development and social outcomes, the team has shown the benefits of early non-parental care and evidenced the moderate efficacy of a multicomponent early intervention program on behavior, cognition and health, in an Irish sample. Team members have developped eHealth tools to be used for MNS in youths, particularly in students. These findings provide key elements to inform public policies and to tailor our experimental interventions.
Research of team members takes advantages of various cohorts including birth cohorts (ex: ELFE and ELDEQ) and young adult cohorts (iShare and CONFINS).
2025 Key Publications
Baggio T, Grecucci A, Crivello F, Joliot M, Tzourio C. Resting state connectivity patterns associated with trait anxiety in adolescence. Sci Rep. 2025;15(1):9711. https://doi.org/10.1038/s41598-025-94790-9
Bailhache M, El-Khoury F, Leproux O, Chazelas E, Gomajee R, Van Der Waerden J, Galera C, Charles MA, Melchior M. Psychological intimate partner violence, child witnessing of parental arguments, and emotional-behavioral outcomes in five-years old: The French ELFE cohort. Child Abuse Negl. 2025;160:107185. https://doi.org/10.1016/j.chiabu.2024.107185
Coelho J, Montagni I, Micoulaud-Franchi J-A, Taillard J, Philip P, Plancoulaine S, Tzourio C. The associations of screen time and physical activity with sleep health during the COVID-19 crisis. Sleep Epidemiol. 2025;5:100119. https://doi.org/10.1016/j.sleepe.2025.100119
Galera C, Navarro MC, Galesne C, Retuerto N, Bentivegna F, Flouri E. Neighborhood green space and psychological distress: a longitudinal study of socioeconomic disparities in mental health outcomes. Environ Int. 2025;204:109799. https://doi.org/10.1016/j.envint.2025.109799
Jean FAM, Montagni I, Schwartz AN, Navarro MC, Galesne C, Macalli M, Cherruaud L, Lerouge-Bailhache M, Cote SM, Tzourio C, Galera C. Illicit substance use and attention deficit hyperactivity disorder symptoms among French university students: a multiple correspondence analysis and a cluster analysis. Eur Arch Psychiatry Clin Neurosci. 2025. https://doi.org/10.1007/s00406-025-02092-y
Kinouani S, Da Cruz H, Simon M, Abraham M, Perret G, Langlois E, Tzourio C. The transition from cigarette smoking to the exclusive or partial use of e-cigarettes: A multi-stage mixed methods study among French university students. Addict Behav. 2025;161:108205. https://doi.org/10.1016/j.addbeh.2024.108205
Kinouani S, Roux F, Questel B, Abraham M, Tzourio C. Reasons for using electronic cigarettes among young adults aged 18 – 30: a systematic review. Excli J. 2025;24:204-37. https://doi.org/10.17179/excli2024-8085
Labrosse D, Vie C, Harb M, Montagni I. Escape Game to Promote Students’ Mental Health Outcomes in the Aftermaths of COVID-19 Pandemic: Protocol for a Mixed Methods Study Evaluating a Cocreated Intervention. JMIR Res Protoc. 2025;14:e64068. https://doi.org/10.2196/64068
Macalli M, Castel L, Jacqmin-Gadda H, Galesne C, Tournier M, Galera C, Pereira E, Tzourio C. Depressive symptoms and suicidal ideation among university students before and after the COVID-19 pandemic. J Affect Disord. 2025;369:149-54. https://doi.org/10.1016/j.jad.2024.09.093
Schwartz A, Galera C, Arsandaux J, Montagni I, Tzourio C. Adverse Childhood Experiences and Illegal Drug Use Among College Students: Findings from a French Sample. Int J Behav Med. 2025;32(2):258-66. https://doi.org/10.1007/s12529-023-10256-0
Last News
A look back at Cédric Galéra's conference at the Collège de France
Focus
Green spaces and mental health – a study conducted by Cédric Galera
Major publication
PUBLIC HEALTH SEMINAR : MELISSA MACALLI 16/01/2026
Evènement
Mélissa Macalli, a BPH young researcher awarded the L'Oréal-UNESCO 2024 Young Talent Prize
Awards & nominations
Study on the mental health of students, 4 years after the lockdown. Effects still struggling to subside
- Press Review
Press
Cocreation and evaluation of an intervention promoting teachers’ mental health literacy: the TEACH-MHE project
Nouveau projet
COMMUNIQUE DE PRESSE :
Une nouvelle étude éclaircit le lien entre les symptômes de TDAH pendant l’enfance et plusieurs comorbidités médicales non psychiatriques
Press
Members
BAILHACHEMarion
Post-doc et Pédiatre PH CHU de BordeauxBourgeoisTiffany
DoctoranteCastelLaura
Ingénieure statisticienneCoteSylvana
DesmaresMarie
Coordinatrice Etudiants Relais PrismeFericelliLisa
Post-doctoranteGaleraCedric
GalesneCharline
DoctoranteKinouaniShérazade
MD, PhDMacalliMelissa
Post-doctorante en Santé Publique, spécialité EpidémiologieMazoyerGarance
Cheffe de projet littératie en santé mentaleMontagniIlaria
MouginMarie
Chef de projets opérationnelsNavarroMarie
Postdoctoral FellowPereiraEdwige
PolletClothilde
chef de projet opérationnelRetuertoNoélia
Ingénieure statisticienneSalamonNicolas
SchwartzAshlyn
Fulbright Doctoral ResearcherSutter-DallayAnne-Laure
MD,PhD,HDRTzourioChristophe
DirecteurViéClara
Chef de projet opérationnel