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Rustand Denis

Chargé de recherche denis.rustand@u-bordeaux.fr

Career path

2025-present: Research Scientist (Chargé de recherche), Bordeaux Population Health Research Center, INSERM U1219, France.

2021-2025: Postdoctoral Researcher, King Abdullah University of Science and Technology (KAUST), Saudi Arabia.

2021: Postdoctoral Researcher, Bordeaux Population Health Research Center, INSERM U1219, France.

2017-2020: Ph.D. in Public Health & Biostatistics, University of Bordeaux, France.

2015-2017: Master of Science in Statistics, University of Southern Brittany, France.

Fonctions

Research Scientist in Biostatistics at Inserm (Chargé de recherche). Member of the BIOSTAT research team.

Publications

  • D. Rustand, J. van Niekerk, E. T. Krainski and H. Rue. Bayesian survival, longitudinal and joint models with INLA. Book in production, 2026.

  • D. Alvares, J. van Niekerk, E. T. Krainski, H. Rue, and D. Rustand. Bayesian survival analysis with INLA. Statistics in Medicine. 2024; 43(20): 3975-4010.

  • D. Rustand, J. van Niekerk, E. T. Krainski, H. Rue & C. Proust-Lima. Fast and flexible inference for joint models of multivariate longitudinal and survival data using Integrated Nested Laplace Approximations. Biostatistics, 2023, kxad019.

  • D. Rustand, L. Briollais, V. Rondeau. A marginal two-part joint model for a longitudinal biomarker and a terminal event with application to advanced head and neck cancers. Pharmaceutical Statistics, 2023. doi: 10.1002/pst.2338.

  • D. Rustand, J. van Niekerk, H. Rue, C. Tournigand, V. Rondeau, L. Briollais. Bayesian Estimation of Two-Part Joint Models for a Longitudinal Semicontinuous Biomarker and a Terminal Event with R-INLA: Interests for Cancer Clinical Trial Evaluation. Biometrical Journal, 2023, 65, 2100322.

  • D. Rustand, L. Briollais, C. Tournigand, V. Rondeau. Two-part joint model for a longitudinal semicontinuous marker and a terminal event with application to metastatic colorectal cancer data. Biostatistics, 2020. 10.1093/biostatistics/kxaa012.

Research Interests

My research focuses on the development of statistical methods for the joint analysis of multivariate longitudinal markers and time-to-event outcomes. I am particularly interested in:

  • Joint Modeling: Developing flexible frameworks for survival and longitudinal data analysis.

  • Bayesian Inference: Integrated Nested Laplace Approximations (INLA) for fast and efficient inference of complex models.

  • Software Development: Author of the INLAjoint R package, facilitating multivariate joint modeling with INLA.

BPH Université de Bordeaux L'inserm