PhD student, Biostatistics

Born in Pau, France in 1993

  • Phd Student, Biostatistics
    INSERM U1219 Bordeaux Population Health, Biostatistics Unit
    Université de Bordeaux
    october 2016 – present
  • MSc in Mathematical Statistics
    Université de Bordeaux
    2014 – 2016
  • BSc in Mathematics
    Université de Pau et des Pays de l’Adour & Université de Bordeaux
    2011 – 2014
  • Baccalauréat in Science, Mathematics Speciality, with honors
    Lycée Louis Barthou, Pau

My PhD research work is done under the supervision of Hélène Jacqmin-Gadda.
I am currently developing inferential methods first to test the existence of a random changepoint in mixed models for longitudinal data and secondly to estimate such model. We particularly focus on application on cognitive ageing in order to describe and better understand the natural evolution of Alzheimer’s Disease.

All statistical methods are implemented into an R package rcpm available on my github page.

Scientific publications

  • Gosse P, Segalas C, Rubin S, Boulestreau R, Jacqmin-Gadda H, Leffondre K, Combe C, Cremer A. Long term evolution of renal function in essential hypertensive patients with no baseline proteinuria. Journal of Human Hypertension. 2019.
  • Segalas C, Amieva H, Jacqmin-Gadda H. A hypothesis testing procedure for random changepoint mixed models. Statistics in Medicine. 2019.

Oral communications

  • july 2019 : Segalas C. Jacqmin-Gadda H., Inferential methods for random changepoint models, 40th annual conference of the ISCB, Leuven, Belgium
  • july 2019 : Segalas C. Jacqmin-Gadda H., Curvilinear bivariate mixed model with random changepoint to compare times of change between cognitive markers in Alzheimer’s disease, 7th IBS Channel Network Conference, Rothamstead Research, UK
  • july 2018 : Segalas C. Jacqmin-Gadda H., Testing the Existence of a Random Changepoint in a Mixed Model, 29th IBC, IBS, Barcelone.
  • 28th may 2018 : Segalas C. Jacqmin-Gadda H., Test de l’existence d’un changement de pente aléatoire dans un modèle mixte, 50th days of statistics, SFDS, Paris.
  • october 2017 : Segalas C. Jacqmin-Gadda H., Test d’un changement de pente aléatoire dans un modèle mixte, Joint days of the research group « statistics and health » and of the french section of IBS, Bordeaux.


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