2014 HDR (Habilitation to conduct research), Univ. Bordeaux, France.
2006 PhD in Biostatistics, Univ. Bordeaux Segalen, France.
2003 Master degree in Epidemiology and Public Health, ISPED, Univ. Bordeaux Segalen, France.
2002 Master degree in Biostatistics, National School for Statistics and Information Analysis, ENSAI, Rennes, France.
2019-… Director of Research (DR2), Inserm, Bordeaux, France.
2008-2019 Researcher (CR1), Inserm, Bordeaux, France.
2008 Research Assistant, Biostatistics and Nutrition departments, Inserm, Bordeaux, France.
2008 Assistant Professor, ISPED, Université Bordeaux Segalen, Bordeaux, France.
2007 Postdoctoral fellow, Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, USA.
2003-2006 Assistant professor, ISPED, Université Bordeaux Segalen, Bordeaux, France.
Joint models, Latent class mixed models, Latent variable models, (Generalized) linear mixed models, Longitudinal analysis of psychometric scales in Masters, summer schools, short courses
Development of dynamic statistical models to describe, explain and predict chronic disease progressions. I specialized in the joint analysis of correlated longitudinal markers and event time history using the so called joint models with applications mainly in neurodegenerative diseases (e.g., Alzheimer’s disease) and cancers. My works often involve latent processes to translate dynamic health phenomena measured by repeated markers, and latent classes to translate the heterogeneity of disease progression. I have also worked on the development of individual dynamic predictions that quantify the risk of experiencing a clinical event based on the dynamic history of an individual. All my works are motivated by epidemiological and clinical questions thanks to strong collaborations with epidemiologists and clinicians, and access to large cohort studies. My developments are made available in R packages with constant maintainance and upgrades.
I serve as Associate Editor for Biometrics (since 2014) and Biostatistics (since 2016).
I belong to the international initiative in Methods in Longitudinal Research in Dementia (MELODEM).
See my github repository and
marqLevAlg: A Parallelized Algorithm for Least-Squares Curve Fitting. R package version 2.0.1.
CInNPL: Causal Inference in a Network of Latent Processes
JLPM: Joint models based on Latent Processes. R package version 1.0
lcmm: Extended Mixed Models Using Latent Classes and Latent Processes. R package version 1.9.4
NormPsy: Normalisation of Psychometric Tests. R package version 1.0.3.