{"id":4712,"date":"2023-10-12T12:39:24","date_gmt":"2023-10-12T10:39:24","guid":{"rendered":"https:\/\/www.bordeaux-population-health.center\/?p=4712"},"modified":"2023-10-13T16:07:32","modified_gmt":"2023-10-13T14:07:32","slug":"publication-of-the-results-of-a-genomic-study-of-cervical-artery-dissection-in-the-journal-of-the-american-college-of-cardiology-by-eleanor-team-cadisp-consortium","status":"publish","type":"post","link":"https:\/\/www.bordeaux-population-health.center\/fr\/publication-of-the-results-of-a-genomic-study-of-cervical-artery-dissection-in-the-journal-of-the-american-college-of-cardiology-by-eleanor-team-cadisp-consortium\/","title":{"rendered":"Publication r\u00e9sultats d’une \u00e9tude g\u00e9nomique sur la dissection des art\u00e8res cervicales dans le Journal of the American College of Cardiology par l’\u00e9quipe ELEANOR & le consortium CADISP"},"content":{"rendered":"

\"\"<\/p>\n

\n

Publication r\u00e9sultats d’une \u00e9tude g\u00e9nomique sur la dissection des art\u00e8res cervicales
\ndans le Journal of the American College of Cardiology
\npar l’\u00e9quipe ELEANOR & le consortium CADISP<\/strong><\/p>\n

La dissection des art\u00e8res cervicales est une cause majeure d\u2019accident vasculaire c\u00e9r\u00e9bral (AVC) isch\u00e9mique chez les jeunes adultes. Elle consiste en un saignement qui survient dans la paroi des art\u00e8res carotides ou vert\u00e9brales et qui va \u00ab d\u00e9chirer \u00bb l\u2019art\u00e8re (d\u2019o\u00f9 le terme de dissection) longitudinalement sans rompre le vaisseau. Ce saignement va engendrer la formation d\u2019un h\u00e9matome qui va diminuer le diam\u00e8tre de l\u2019art\u00e8re et potentiellement entra\u00eener son obturation, provoquant un AVC isch\u00e9mique.<\/p>\n

\nLes r\u00e9sultats d’une \u00e9tude g\u00e9nomique sur la dissection des art\u00e8res cervicales, coordonn\u00e9e par des chercheurs de l’\u00e9quipe ELEANOR<\/a> et du consortium CADISP, ont \u00e9t\u00e9 publi\u00e9s dans le Journal of the American College of Cardiology (JACC<\/a>).\n<\/p>\n

L’association des facteurs de risque vasculaires avec la dissection des art\u00e8res cervicales, une cause majeure d’accident vasculaire c\u00e9r\u00e9bral (AVC) isch\u00e9mique chez l\u2019adulte jeune, a longtemps \u00e9t\u00e9 controvers\u00e9e.
Il n’existe actuellement aucune recommandation sur l’\u00e9valuation et la prise en charge des facteurs de risque vasculaires chez les patients souffrant de dissections des art\u00e8res cervicales.
Bas\u00e9s sur des approches de randomisation mend\u00e9lienne, les r\u00e9sultats de cette \u00e9tude confirment une forte association entre une pression art\u00e9rielle \u00e9lev\u00e9e et le risque de dissection.
Des instruments g\u00e9n\u00e9tiques simulant l\u2019effet antihypertenseur des \u03b2-bloquants \u00e9taient \u00e9galement associ\u00e9s \u00e0 un risque plus faible de dissection, mais pas d\u2019AVC isch\u00e9mique sans dissection.<\/p>\n

\"\"<\/p>\n

Ces r\u00e9sultats pourraient contribuer \u00e0 l\u2019\u00e9laboration de recommandations concernant la surveillance de la pression art\u00e9rielle apr\u00e8s une dissection des art\u00e8res cervicales et \u00e0 la mise en place d’essais cliniques pour la pr\u00e9vention secondaire des dissections des art\u00e8res cervicales, en particulier pour l’\u00e9valuation des traitements antihypertenseurs.<\/p>\n

=> Acc\u00e8s \u00e0 la publication sur le Journal of the American College of Cardiology<\/a> (JACC)<\/p>\n

\nContact<\/span>
\nPr. St\u00e9phanie Debette<\/strong>
\nUniversit\u00e9 de Bordeaux, Inserm, Centre de recherche en sant\u00e9 des populations de Bordeaux, UMR 1219
\nService de neurologie, CHU de Bordeaux
\n146, rue L\u00e9o Saignat, 33076 Bordeaux, France
\nMail : stephanie.debette@u-bordeaux.fr\n<\/p>\n

\"\"<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Publication r\u00e9sultats d’une \u00e9tude g\u00e9nomique sur la dissection des art\u00e8res cervicales dans le Journal of the American College of Cardiology par l’\u00e9quipe ELEANOR & le consortium CADISP La dissection des art\u00e8res cervicales est une cause majeure d\u2019accident vasculaire c\u00e9r\u00e9bral (AVC) isch\u00e9mique chez les jeunes adultes. Elle consiste en un saignement qui survient dans la paroi […]<\/p>\n","protected":false},"author":613,"featured_media":4679,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[24],"tags":[],"class_list":["post-4712","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualites-du-centre"],"acf":[],"yoast_head":"\nPublication r\u00e9sultats d'une \u00e9tude g\u00e9nomique sur la dissection des art\u00e8res cervicales dans le Journal of the American College of Cardiology par l'\u00e9quipe ELEANOR & le consortium CADISP | Bordeaux population health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.bordeaux-population-health.center\/fr\/publication-of-the-results-of-a-genomic-study-of-cervical-artery-dissection-in-the-journal-of-the-american-college-of-cardiology-by-eleanor-team-cadisp-consortium\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publication r\u00e9sultats d'une \u00e9tude g\u00e9nomique sur la dissection des art\u00e8res cervicales dans le Journal of the American College of Cardiology par l'\u00e9quipe ELEANOR & le consortium CADISP | Bordeaux population health\" \/>\n<meta property=\"og:description\" content=\"Publication r\u00e9sultats d’une \u00e9tude g\u00e9nomique sur la dissection des art\u00e8res cervicales dans le Journal of the American College of Cardiology par l’\u00e9quipe ELEANOR & le consortium CADISP La dissection des art\u00e8res cervicales est une cause majeure d\u2019accident vasculaire c\u00e9r\u00e9bral (AVC) isch\u00e9mique chez les jeunes adultes. 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