{"id":4180,"date":"2023-07-10T12:40:24","date_gmt":"2023-07-10T10:40:24","guid":{"rendered":"https:\/\/www.bordeaux-population-health.center\/?p=4180"},"modified":"2023-07-11T13:06:11","modified_gmt":"2023-07-11T11:06:11","slug":"publication-association-sexe-genre-et-declin-cognitif","status":"publish","type":"post","link":"https:\/\/www.bordeaux-population-health.center\/fr\/publication-association-sexe-genre-et-declin-cognitif\/","title":{"rendered":"Une publication sur l’association entre le sexe\/genre et le d\u00e9clin cognitif a remport\u00e9 le prix de la publication de l’ann\u00e9e 2023"},"content":{"rendered":"
\n

\"\"
\nUne publication sur l’association entre le sexe\/genre et le d\u00e9clin cognitif
a remport\u00e9 le prix de la publication de l’ann\u00e9e 2023<\/strong><\/p>\n

\n

L’International Society to Advance Alzheimer’s Research and Treatment<\/a> Design and Data Analytics PIA a s\u00e9lectionn\u00e9 la publication intitul\u00e9e \u00ab\u00a0How Selection Over Time Contributes to the Inconsistency of the Association Between Sex\/Gender and Cognitive Decline Across Cognitive Aging Cohorts\u00a0\u00bb publi\u00e9e dans l’American Journal of Epidemiology comme laur\u00e9ate du prix de la publication de l’ann\u00e9e 2023.<\/strong><\/p>\n

L’association entre le sexe\/genre et le d\u00e9clin cognitif li\u00e9 au vieillissement reste mal comprise en raison de r\u00e9sultats contradictoires dans la litt\u00e9rature. Cette disparit\u00e9 peut s\u2019expliquer par la diversit\u00e9 des fonctions cognitives \u00e9tudi\u00e9es et des caract\u00e9ristiques des populations \u00e9tudi\u00e9es, mais aussi par une s\u00e9lection diff\u00e9rentielle entre les hommes et les femmes d\u00fbe \u00e0 la sortie d\u2019\u00e9tude et le d\u00e9c\u00e8s.
\nLa pr\u00e9sente \u00e9tude, initi\u00e9e lors de la r\u00e9union annuelle 2018 de l’initiative MELODEM<\/a><\/strong> (MEthods in LOngitudinal DEMentia research), a pour objectif d’\u00e9valuer l’impact de la s\u00e9lection par la sortie et le d\u00e9c\u00e8s sur l’association entre le sexe\/genre et le d\u00e9clin cognitif. l’association entre le sexe\/genre et le d\u00e9clin cognitif.<\/div>\n
Nous avons d’abord compar\u00e9 les m\u00e9thodes statistiques pour donn\u00e9es longitudinales les plus fr\u00e9quemment utilis\u00e9es, ciblant soit des estimants populationnels (mod\u00e8les marginaux estim\u00e9s par \u00e9quations d’estimation g\u00e9n\u00e9ralis\u00e9es), soit les estimants sp\u00e9cifiques aux sujets (mod\u00e8les mixtes\/conjoints estim\u00e9s par maximum de vraisemblance) dans 8 \u00e9tudes sur le vieillissement : 6 cohortes populationnelles (ACTIVE (1), PAQUID (2), REGARDS (3), 3Cit\u00e9s-Bordeaux (4), WHICAP (5) Whitehall II (6)) et 2 \u00e9tudes cliniques (ADNI (7), MEMENTO (8)).
\nNous illustrons les diff\u00e9rences entre estimateurs de l’association entre le sexe\/genre et le d\u00e9clin cognitif \u00e0 partir d’exemples s\u00e9lectionn\u00e9s et soulignons le r\u00f4le crucial de la s\u00e9lection diff\u00e9rentielle par la sortie d\u2019\u00e9tude et le d\u00e9c\u00e8s.
\nEn utilisant le m\u00eame estimateur, nous contrastons ensuite les associations entre le sexe\/genre et le d\u00e9clin cognitif entre les cohortes et les mesures cognitives, sugg\u00e9rant une association diff\u00e9rentielle r\u00e9siduelle entre le sexe\/genre en fonction de la mesure cognitive cibl\u00e9e (m\u00e9moire ou fluence animale) et de la s\u00e9lection de cohorte initiale.
\nNous recommandons de cibler les estimants sp\u00e9cifiques aux sujets dans la population vivante pour \u00e9valuer les diff\u00e9rences entre les sexes\/genres tout en tenant compte de la s\u00e9lection diff\u00e9rentielle au fil du temps.<\/div>\n

Lien vers la publication<\/strong><\/p>\n

https:\/\/academic.oup.com\/aje\/article\/191\/3\/441\/6370352<\/strong><\/a><\/p>\n

R\u00e9f\u00e9rences<\/strong><\/p>\n

1. Jobe JB, Smith DM, Ball K, et al. ACTIVE: a cognitive intervention trial to promote independence in older adults. Control Clin Trials. 2001; 22(4):453\u2013479.
\n2. Letenneur L, Commenges D, Dartigues J-F, et al. Incidence of dementia and Alzheimer\u2019s disease in elderly community residents of south-western France. Int J Epidemiol. 1994; 23(6):1256\u20131261
\n3. Howard VJ, Cushman M, Pulley LV, et al. The Reasons for Geographic and Racial Differences in Stroke Study: objectives and design. Neuroepidemiology. 2005;25(3): 135\u2013143.
\n4. Study Group. Vascular factors and risk of dementia: design of the Three-City Study and baseline characteristics of the study population. Neuroepidemiology. 2003;22(6):316\u2013325.
\n5. Tang M-X, Cross P, Andrews H, et al. Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan. Neurology. 2001;56(1):49\u201356.
\n6. Marmot MG, Smith GD, Stansfeld S, et al. Health inequalities among British civil servants: the Whitehall II Study. Lancet. 1991;337(8754):1387\u20131393.
\n7. Mueller SG, Weiner MW, Thal LJ, et al. Ways toward an early diagnosis in Alzheimer\u2019s disease: the Alzheimer\u2019s Disease Neuroimaging Initiative (ADNI). Alzheimers Dement. 2005;1(1):55\u201366.
\n8. Dufouil C, Dubois B, Vellas B, et al. Cognitive and imaging markers in non-demented subjects attending a memory clinic: study design and baseline findings of the MEMENTO cohort. Alzheimer\u2019s Res Ther. 2017;9(1):67.<\/p>\n

Contact<\/strong><\/p>\n

Anais Rouanet anais.rouanet@u-bordeaux.fr<\/strong>
\nCecile Proust-Lima cecile.proust-lima@u-bordeaux.fr<\/strong><\/p>\n<\/div>\n

\"\"<\/a><\/p>\n<\/div>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Une publication sur l’association entre le sexe\/genre et le d\u00e9clin cognitifa remport\u00e9 le prix de la publication de l’ann\u00e9e 2023 L’International Society to Advance Alzheimer’s Research and Treatment Design and Data Analytics PIA a s\u00e9lectionn\u00e9 la publication intitul\u00e9e \u00ab\u00a0How Selection Over Time Contributes to the Inconsistency of the Association Between Sex\/Gender and Cognitive Decline Across […]<\/p>\n","protected":false},"author":613,"featured_media":4175,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[25],"tags":[],"class_list":["post-4180","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-revue-de-presse"],"acf":[],"yoast_head":"\nUne publication sur l'association entre le sexe\/genre et le d\u00e9clin cognitif a remport\u00e9 le prix de la publication de l'ann\u00e9e 2023 | Bordeaux 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