{"id":2506,"date":"2023-02-28T17:04:40","date_gmt":"2023-02-28T16:04:40","guid":{"rendered":"https:\/\/www.bordeaux-population-health.center\/?p=2506"},"modified":"2023-05-04T18:15:37","modified_gmt":"2023-05-04T16:15:37","slug":"publication-optima-clinical-trial-eclinicalmedicine","status":"publish","type":"post","link":"https:\/\/www.bordeaux-population-health.center\/fr\/publication-optima-clinical-trial-eclinicalmedicine\/","title":{"rendered":"Publication de l’essai clinique OptiMA dans eClinicalMedicine concernant les enfants les plus s\u00e9v\u00e8rement malnutris"},"content":{"rendered":"
\n

\"\"<\/p>\n

Publication de l’essai clinique OptiMA dans eClinicalMedicine
\nconcernant les enfants les plus s\u00e9v\u00e8rement malnutris<\/strong><\/p>\n

\n

L\u2019\u00e9quipe GHiGS<\/a>, en partenariat avec l\u2019ONG humanitaire ALIMA<\/a> et le Programme National Nutrition de la R\u00e9publique d\u00e9mocratique du Congo (RdC), a mis en oeuvre dans le Kasa\u00ef en RdC un essai clinique randomis\u00e9<\/strong> destin\u00e9 \u00e0 \u00e9valuer une nouvelle strat\u00e9gie<\/strong> appel\u00e9e \u00ab OptiMA \u00bb.<\/p>\n

Dans cet essai, les enfants<\/strong> souffrant de malnutrition aigu\u00eb<\/strong>, quel que soit le stade de la maladie, recevaient un unique traitement nutritionnel<\/strong>, les aliments th\u00e9rapeutiques pr\u00eats \u00e0 l\u2019emploi (ATPE)<\/strong>, selon un dosage progressivement d\u00e9gressif au fur et \u00e0 mesure de la r\u00e9cup\u00e9ration nutritionnelle.<\/p>\n

=> Les r\u00e9sultats<\/strong> d\u00e9montrant la sup\u00e9riorit\u00e9 de cette strat\u00e9gie au global avaient \u00e9t\u00e9 publi\u00e9s l\u2019an pass\u00e9 dans The Lancet Global Health<\/strong> : https:\/\/www.thelancet.com\/journals\/langlo\/article\/PIIS2214-109X(22)00041-9\/fulltext<\/a>.<\/p>\n

Un deuxi\u00e8me article majeur<\/strong> autour de cet essai clinique a \u00e9t\u00e9 publi\u00e9 aujourd\u2019hui dans eClinicalMedicine<\/strong> en se focalisant<\/strong> cette fois chez les enfants les plus s\u00e9v\u00e8rement malnutris<\/strong>.
\nBien que ces enfants pris en charge suivant la strat\u00e9gie OptiMA aient re\u00e7us moins d\u2019ATPE<\/strong> dans leur prise en charge, ils ont \u00e9t\u00e9 gu\u00e9ris \u00e0 96%<\/strong>, de fa\u00e7on non-inf\u00e9rieure \u00e0 la prise en charge actuelle.<\/p>\n

Ces r\u00e9sultats importants d\u00e9montrent l\u2019innocuit\u00e9<\/strong> de la prise en charge de la malnutrition aigu\u00eb des enfants selon un dosage progressivement d\u00e9gressif des ATPE<\/strong> au fur et \u00e0 mesure de la r\u00e9cup\u00e9ration nutritionnelle, dans un contexte de forte ins\u00e9curit\u00e9 alimentaire.<\/p>\n

Contact :
\nRenaud Becquet\u00a0\u00a0–\u00a0 renaud.becquet@u-bordeaux.fr
\n<\/strong><\/p>\n

=> Acc\u00e8s \u00e0 la publication eClinicalMedicine<\/a><\/strong><\/p>\n

\"\"<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Publication de l’essai clinique OptiMA dans eClinicalMedicine concernant les enfants les plus s\u00e9v\u00e8rement malnutris L\u2019\u00e9quipe GHiGS, en partenariat avec l\u2019ONG humanitaire ALIMA et le Programme National Nutrition de la R\u00e9publique d\u00e9mocratique du Congo (RdC), a mis en oeuvre dans le Kasa\u00ef en RdC un essai clinique randomis\u00e9 destin\u00e9 \u00e0 \u00e9valuer une nouvelle strat\u00e9gie appel\u00e9e \u00ab […]<\/p>\n","protected":false},"author":613,"featured_media":2509,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[25],"tags":[],"class_list":["post-2506","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-revue-de-presse"],"acf":[],"yoast_head":"\nPublication de l'essai clinique OptiMA dans eClinicalMedicine concernant les enfants les plus s\u00e9v\u00e8rement malnutris | Bordeaux population 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