{"id":2338,"date":"2022-10-04T10:10:29","date_gmt":"2022-10-04T08:10:29","guid":{"rendered":"https:\/\/www.bordeaux-population-health.center\/une-vaste-etude-genomique-internationale-sur-les-accidents-vasculaires-cerebraux-avc-ouvre-de-nouvelles-perspectives-en-termes-dinnovation-therapeutique-et-de-prediction-de-risque\/"},"modified":"2022-10-04T10:10:29","modified_gmt":"2022-10-04T08:10:29","slug":"une-vaste-etude-genomique-internationale-sur-les-accidents-vasculaires-cerebraux-avc-ouvre-de-nouvelles-perspectives-en-termes-dinnovation-therapeutique-et-de-prediction-de-risque","status":"publish","type":"post","link":"https:\/\/www.bordeaux-population-health.center\/fr\/une-vaste-etude-genomique-internationale-sur-les-accidents-vasculaires-cerebraux-avc-ouvre-de-nouvelles-perspectives-en-termes-dinnovation-therapeutique-et-de-prediction-de-risque\/","title":{"rendered":"Une vaste \u00e9tude g\u00e9nomique internationale sur les accidents vasculaires c\u00e9r\u00e9braux (AVC) ouvre de nouvelles perspectives en termes d\u2019innovation th\u00e9rapeutique et de pr\u00e9diction de risque."},"content":{"rendered":"

\"\"
\nAlors que l\u2019AVC est la deuxi\u00e8me cause de d\u00e9c\u00e8s dans le monde, la plus grande \u00e9tude g\u00e9nomique jamais r\u00e9alis\u00e9e sur les AVC vient de r\u00e9v\u00e9ler des informations majeures publi\u00e9es dans Nature le 28 septembre.
\nPortant sur plus de 200 000 patients victimes d’AVC et plus de 2 millions d’individus t\u00e9moins d\u2019origines g\u00e9ographiques tr\u00e8s diverses, ces recherches ont permis d\u2019identifier de nouveaux g\u00e8nes impliqu\u00e9s dans la gen\u00e8se des AVC. Ceci a permis la d\u00e9couverte de nouvelles cibles th\u00e9rapeutiques potentielles et l\u2019identification de populations \u00e0 haut risque d\u2019AVC du fait de leur patrimoine g\u00e9n\u00e9tique.
\nCe travail est le r\u00e9sultat d\u2019une collaboration au travers du consortium GIGASTROKE impliquant de nombreux chercheurs et r\u00e9seaux internationaux. Il d\u00e9montre la puissance de la g\u00e9nomique pour d\u00e9velopper des approches innovantes et constitue une \u00e9tape suppl\u00e9mentaire vers des strat\u00e9gies de pr\u00e9vention de pr\u00e9cision et d\u2019innovation th\u00e9rapeutique pour les AVC.<\/p>\n

Article :
\nStroke genetics informs drug discovery and risk prediction across ancestries (2022). Aniket Mishra, Rainer Malik, Tsuyoshi Hachiya, Tuuli J\u00fcrgenson, Shinichi Namba, Daniel C. Posner, et al. Nature. doi: 10.1038\/s41586-022-05165-3
\nAcc\u00e9der au communiqu\u00e9 de presse<\/a><\/span><\/strong><\/p>\n

Contact :
\nPr. Stephanie Debette stephanie.debette@u-bordeaux.fr
\nDr. Aniket Mishra aniket.mishra@u-bordeaux.fr
\n<\/strong><\/p>\n

En savoir plus sur les auteurs<\/strong><\/p>\n

\"\"
\nCe travail, dont le premier auteur est Dr Aniket Mishra (jeune chercheur dans l\u2019\u00e9quipe ELEANOR), a \u00e9t\u00e9 coordonn\u00e9 par le BPH (St\u00e9phanie Debette), avec le centre de recherche l’Institute for Stroke and Dementia Research de l’Universit\u00e9 Ludwig-Maximilian de Munich (LMU, Allemagne), et men\u00e9 par des membres du consortium GIGASTROKE, impliquant de nombreux consortiums tels que l’ISGC<\/a> (Internation Stroke Genetics consortium) et CHARGE<\/a> (Cohorts for Heart and Aging Research in Genomic Epidemiology), et des chercheurs de plus de 20 pays avec notamment des unit\u00e9s de recherche de l’Universit\u00e9 de Tokyo (Japon), l’Universit\u00e9 de Tartu (Estonie), l’Universit\u00e9 d’Ibadan (Nigeria), le Veteran Affairs Boston Healthcare System et Harvard Medical School (\u00c9tats-Unis) en co-leadership.<\/p>\n","protected":false},"excerpt":{"rendered":"

Alors que l\u2019AVC est la deuxi\u00e8me cause de d\u00e9c\u00e8s dans le monde, la plus grande \u00e9tude g\u00e9nomique jamais r\u00e9alis\u00e9e sur les AVC vient de r\u00e9v\u00e9ler des informations majeures publi\u00e9es dans Nature le 28 septembre. Portant sur plus de 200 000 patients victimes d’AVC et plus de 2 millions d’individus t\u00e9moins d\u2019origines g\u00e9ographiques tr\u00e8s diverses, ces […]<\/p>\n","protected":false},"author":613,"featured_media":1683,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[25],"tags":[],"class_list":["post-2338","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-revue-de-presse"],"acf":[],"yoast_head":"\nUne vaste \u00e9tude g\u00e9nomique internationale sur les accidents vasculaires c\u00e9r\u00e9braux (AVC) ouvre de nouvelles perspectives en termes d\u2019innovation th\u00e9rapeutique et de pr\u00e9diction de risque. | Bordeaux population health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.bordeaux-population-health.center\/fr\/une-vaste-etude-genomique-internationale-sur-les-accidents-vasculaires-cerebraux-avc-ouvre-de-nouvelles-perspectives-en-termes-dinnovation-therapeutique-et-de-prediction-de-risque\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Une vaste \u00e9tude g\u00e9nomique internationale sur les accidents vasculaires c\u00e9r\u00e9braux (AVC) ouvre de nouvelles perspectives en termes d\u2019innovation th\u00e9rapeutique et de pr\u00e9diction de risque. | Bordeaux population health\" \/>\n<meta property=\"og:description\" content=\"Alors que l\u2019AVC est la deuxi\u00e8me cause de d\u00e9c\u00e8s dans le monde, la plus grande \u00e9tude g\u00e9nomique jamais r\u00e9alis\u00e9e sur les AVC vient de r\u00e9v\u00e9ler des informations majeures publi\u00e9es dans Nature le 28 septembre. 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