{"id":14810,"date":"2026-10-12T10:05:33","date_gmt":"2026-10-12T08:05:33","guid":{"rendered":"https:\/\/www.bordeaux-population-health.center\/?p=14810"},"modified":"2026-10-12T10:24:05","modified_gmt":"2026-10-12T08:24:05","slug":"bordeaux-point-dattache-international-pour-un-symposium-sur-lexposome-et-la-sante-du-cerveau","status":"publish","type":"post","link":"https:\/\/www.bordeaux-population-health.center\/fr\/bordeaux-point-dattache-international-pour-un-symposium-sur-lexposome-et-la-sante-du-cerveau\/","title":{"rendered":"Bordeaux, point d\u2019attache international pour un symposium sur l\u2019exposome et la sant\u00e9 du cerveau"},"content":{"rendered":"

Du 17 au 19 juin 2026, Bordeaux a accueilli le 2026 Global Exposome Symposium for Brain Health consacr\u00e9 au th\u00e8me \u00ab Mapping the Exposome to Prevent Alzheimer\u2019s Disease and Related Dementias \u00bb.<\/h3>\n

Pour la communaut\u00e9 bordelaise et fran\u00e7aise de recherche en sant\u00e9 environnementale, cet \u00e9v\u00e9nement a permis de mettre en lumi\u00e8re Bordeaux comme un lieu d\u2019expertise sur l\u2019exposome, la sant\u00e9 des populations et la pr\u00e9vention des maladies neurod\u00e9g\u00e9n\u00e9ratives.<\/h3>\n

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Ce 11e Symposium Exposome organis\u00e9 par Mount Sinai, le premier en France, \u00e9tait co-organis\u00e9 par l\u2019Institute for Exposomic Research et le Brookdale Department of Geriatrics and Palliative Medicine de l\u2019Icahn School of Medicine at Mount Sinai, ainsi que l\u2019universit\u00e9 de Bordeaux et l\u2019Inserm, et ambitionnait de r\u00e9unir et construire une communaut\u00e9 mondiale sur exposome.\u00a0<\/span><\/p>\n

Pendant trois jours, plus de 140 chercheurs, cliniciens, jeunes scientifiques et acteurs de sant\u00e9 publique venus de 20 pays ont \u00e9chang\u00e9 sur le r\u00f4le des expositions environnementales tout au long de la vie dans le risque de maladie d\u2019Alzheimer et des d\u00e9mences apparent\u00e9es<\/b>.\u00a0<\/span><\/p>\n

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L’influence de l’exposome sur la sant\u00e9 c\u00e9r\u00e9brale est un th\u00e8me de recherche fort au BPH <\/b><\/span><\/h3>\n

Parmi les intervenants plusieurs membres du BPH ont pu partager leurs travaux et leurs expertises.<\/p>\n

Tous ces \u00e9changes enrichissants entre les communaut\u00e9s scientifiques font progresser vers une meilleure compr\u00e9hension des facteurs environnementaux influen\u00e7ant les maladies neurod\u00e9g\u00e9n\u00e9ratives.\u00a0<\/span><\/p>\n

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Comprendre cette notion d\u2019exposome <\/b><\/span><\/h3>\n

L\u2019exposome d\u00e9signe l\u2019ensemble des expositions environnementales auxquelles un individu est soumis au cours de sa vie : pollution de l\u2019air, alimentation, sommeil, conditions de travail, d\u00e9terminants sociaux, microbiote ou encore stress. Le symposium a mis en avant l\u2019enjeu central de la recherche actuelle : ne plus \u00e9tudier ces facteurs isol\u00e9ment, mais saisir leurs combinaisons, leurs interactions et leurs effets cumul\u00e9s sur la sant\u00e9 c\u00e9r\u00e9brale.\u00a0<\/span><\/p>\n

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La recherche sur l\u2019exposome pour pr\u00e9venir et pour comprendre des pathologies notamment du cerveau<\/b><\/span><\/h3>\n

Les interventions ont explor\u00e9 notamment les origines d\u00e9veloppementales de la maladie d\u2019Alzheimer, le lien entre nutrition et cognition, le sommeil et la neurod\u00e9g\u00e9n\u00e9rescence, les m\u00e9langes d\u2019expositions pendant la grossesse, ainsi que l\u2019axe microbiote-intestin-cerveau.\u00a0<\/span><\/p>\n

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Des technologies au service de la pr\u00e9vention<\/b><\/span><\/h3>\n

Le programme a \u00e9galement mis en lumi\u00e8re les avanc\u00e9es m\u00e9thodologiques n\u00e9cessaire pour mieux explorer l\u2019exposome : mod\u00e9lisation statistique, mod\u00e9lisation g\u00e9ospatiale, analyse m\u00e9tabolomique \u00e0 haute r\u00e9solution, analyses chimiques non cibl\u00e9es, capteurs portables, et autres \u00e9tudes d\u2019association \u00e0 l\u2019\u00e9chelle de l\u2019exposome (EWAS) introduites gr\u00e2ce avec l\u2019intelligence artificielle.\u00a0<\/span><\/p>\n

Ces approches ouvrent la voie \u00e0 une pr\u00e9vention de pr\u00e9cision<\/b> : identifier plus t\u00f4t des signatures mol\u00e9culaires et des profils de risque, afin de proposer des interventions avant l\u2019apparition des sympt\u00f4mes.\u00a0<\/span><\/p>\n

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Une communaut\u00e9 scientifique qui se structure<\/b><\/span><\/h3>\n

Avec une trentaine d\u2019intervenants, deux tables rondes et 50 communications par affiche, le symposium a favoris\u00e9 les \u00e9changes entre \u00e9pid\u00e9miologie environnementale, g\u00e9riatrie, neurologie, toxicologie, sant\u00e9 publique et sciences computationnelles.\u00a0<\/span><\/p>\n

Parmi les interventions des membres du BPH comme C\u00e9cilia Samieri<\/b> [co-responsable de l\u2019\u00e9quipe BPH-ELEANOR] sur les expositions chimiques impliqu\u00e9es dans le vieillissement c\u00e9r\u00e9bral et les d\u00e9mences et Carole Dufouil<\/b> [responsable de l\u2019\u00e9quipe BPH-PHARes] sur les biomarqueurs pr\u00e9coces, des avanc\u00e9es diagnostiques et des opportunit\u00e9s d\u2019int\u00e9gration de l\u2019exposomique.<\/p>\n

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La rel\u00e8ve scientifique<\/b><\/span><\/h3>\n

15 jeunes chercheurs et enseignants-chercheurs en d\u00e9but de carri\u00e8re, issus de huit pays, ont b\u00e9n\u00e9fici\u00e9 de bourses de mobilit\u00e9 pour pr\u00e9senter leurs travaux. Les affiches prim\u00e9es ont notamment r\u00e9compens\u00e9 des recherches sur les scores pr\u00e9dictifs de risque de d\u00e9mence, les relations alimentation-m\u00e9tabolome et le vieillissement biologique.<\/p>\n

Parmi eux Ima Bernada <\/b>doctorante de l\u2019\u00e9quipe BPH-ELEANOR sous la direction de David-Alexandre Tr\u00e9gou\u00ebt<\/b> a re\u00e7u un prix pour son affiche \u2018Cartographie des relations diet-m\u00e9tabolome avec des m\u00e9thodes de r\u00e9seau en relation avec le d\u00e9clin cognitif ult\u00e9rieur chez les personnes \u00e2g\u00e9es\u2019<\/p>\n

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Les chercheures et chercheurs se sont donn\u00e9 rendez-vous du 24 au 27 mai 2027 au Maroc<\/a>, pour la prochaine \u00e9dition du symposium consacr\u00e9 \u00e0 l\u2019exposome et aux maladies d\u2019Alzheimer et apparent\u00e9es.\u00a0<\/span><\/p>\n

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En savoir plus<\/div>\n

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Les pr\u00e9sentations qui ont \u00e9t\u00e9 diffus\u00e9es en direct \u00e0 plus de 300 spectateurs, et les enregistrements ainsi que le livret scientifique complet<\/a> \u2014 programme et r\u00e9sum\u00e9s des 50 affiches \u2014 sont disponibles en ligne\u00a0: 2026 Global Exposomics for Brain Health Symposium – YouTube<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Du 17 au 19 juin 2026, Bordeaux a accueilli le 2026 Global Exposome Symposium for Brain Health consacr\u00e9 au th\u00e8me \u00ab Mapping the Exposome to Prevent Alzheimer\u2019s Disease and Related Dementias \u00bb. Pour la communaut\u00e9 bordelaise et fran\u00e7aise de recherche en sant\u00e9 environnementale, cet \u00e9v\u00e9nement a permis de mettre en lumi\u00e8re Bordeaux comme un lieu […]<\/p>\n","protected":false},"author":1419,"featured_media":14817,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[58],"tags":[],"class_list":["post-14810","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evenement"],"acf":[],"yoast_head":"\nBordeaux, point d\u2019attache international pour un symposium sur l\u2019exposome et la sant\u00e9 du cerveau | Bordeaux population health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.bordeaux-population-health.center\/fr\/bordeaux-point-dattache-international-pour-un-symposium-sur-lexposome-et-la-sante-du-cerveau\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bordeaux, point d\u2019attache international pour un symposium sur l\u2019exposome et la sant\u00e9 du cerveau | Bordeaux population health\" \/>\n<meta property=\"og:description\" content=\"Du 17 au 19 juin 2026, Bordeaux a accueilli le 2026 Global Exposome Symposium for Brain Health consacr\u00e9 au th\u00e8me \u00ab Mapping the Exposome to Prevent Alzheimer\u2019s Disease and Related Dementias \u00bb. 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