The projects carried out within the HEALTHY “Health, well-being and achievement in the young “ team associate the research fields of Social and Human Sciences (i.e. psychology, communication, anthropology) with epidemiology in order to explore the biomedical and psychosocial determinants of youth health.
The HEALTHY team consists of permanent researchers in neuroepidemiology and psychopathology, post-doctoral researchers, PhD students, statisticians, engineers and technical and methodological support staff.
Objectives
The research conducted by the HEALTHY team is based on the fact that a few dated are available on the health of young people, from infancy to early adulthood. We collect and analyse data on health, socio-demographic conditions, biological aspects, academic achievement etc. The first objective is to cover the lack of information on a population often confronted with situations and diseases causing serious complications and inconveniences in daily life.
The second objective is to design and implement intervention approaches to test specific programs to improve the health of young people. The interventions are carried out on young cohorts available to the team (ex. i-Share). The HEALTHY team is particularly interested in the feasibility and evaluation of such interventions.
The HEALTHY team mainly conducts surveys in the form of on- and off-line questionnaires, interviews and focus groups. Interventions are also conducted on schoolchildren and students from higher education. Finally, bio-imaging is used to assess the risk factors, the involvement of structural brain lesions, the endovascular function, and the neuropsychological performance in the young.
Research areas
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The health of students: the i-Share cohort
The first axis of our research is based on the i-Share (internet-based Students HeAlth Research Enterprise) study on the health and well-being of French higher education students. During this crucial period of life the personal behaviors and the social and academic environments cans lead to the onset of different diseases. Some members of the HEALTHY team are interested in collecting and analyzing data on the health of thousands of students in order to assess the frequency and impact of several diseases and to study in depth their pathophysiological and psychopathological mechanisms.
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The health of children
The second axis of our research is oriented towards the health of schoolchildren (primary and secondary school). We are particularly interested in studying the factors associated with stress and attention deficit disorder and hyperactivity, and their health effects (psychopathological symptoms, risk behavior, migraine) in the short and the long term.
Main publications
- Kurth T, Mohamed S, Maillard P, Zhu YC, Chabriat H, Mazoyer B, Bousser MG, Dufouil C, Tzourio C. Headache, migraine, and structural brain lesions and function: the population-based EVA MRI study. BMJ 2011; 342:c7357. This paper links not only migraine but severe headache in general with white matter hyperintensity on the population level and further shows an association between migraine and infarct lesion in specific brain regions.
- Chasman DI, Schürks M, Anttila V, [+18 coauthors], Kurth T. Genome-wide association study reveals three susceptibility loci for common migraine in the general population. Nat Genetics 2011; 43(7):695-8. This paper has identified for the first time three genetic loci for the common form of migraine on the population level.
- Galéra C, Côté SM, Bouvard MP, Pingault JB, Melchior M, Michel G, Boivin M, Tremblay RE. Early risk factors for hyperactivity impulsivity and inattention trajectories from age 17 months to 8 years. Arch Gen Psychiatry. 2011 Dec;68(12):1267-75. This paper has identified early risk factors (cf.; prenatal, perinatal social, and parental psychopathology variables), act independently to heighten the likelihood of having persistently high levels of hyperactivity-impulsivity and inattention symptoms from infancy to middle childhood.
- Salla, J., Michel, G., Pingault, J. B., Lacourse, E., Paquin, S., Galéra, C., Falissard, B., Boivin, M., Tremblay, R. E. & Côté, S. M. (2016). Childhood trajectories of inattention-hyperactivity and academic achievement at 12 years. European Child & Adolescent Psychiatry, 1-12.
- Tzourio C, Laurent S, Debette S. Is hypertension associated with an accelerated aging of the brain? Hypertension 2014; 257(8):894-903. In a systematic review several key factors of brain aging are linked to hypertension, also in middle aged individuals.
Details
Centre de recherche INSERM U1219
Université de Bordeaux, ISPED case 11
146 rue Léo-Saignat 33076 BORDEAUX cedex
Tél : +33 (0)5 57 57 16 59
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Centre de recherche INSERM U1219
Psychologie clinique, psychopathologie
Bureau 5 Bât A. / ENTRESOL
3 Ter place de la Victoire 33076 BORDEAUX cedex
Tél : +33 (0)5 57 57 18 30
